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The activity of rabbit antisera against nu/nu BALB/c lymphocytes was estimated in vivo and in vitro. It was found that anti-lymphocyte serum (ALS) against nu/nu lymph node cells suppressed the alloantigen reaction and the spontaneous rosette-forming cell (sRFC) or plaque-forming cell (PFC) formation for T-dependent (sheep red blood cells) and T-independent (lipopolysaccharide) antigens. ALS against nu/nu spleen cells affected only the sRFC and PFC for T-independent antigen. The former serum exhibited a high cytotoxicity for the suspensions enriched or depleted in B cells, while the latter was more cytotoxic for the suspension enriched in B cells. This may indicate that ALS anti-nu/nu spleen cells is specific for B lymphocytes, and ALS anti nu/nu lymph node cells is directed not only to B cells but also to a subpopulation of T lymphocytes. It may suggest the existence of a subpopulation of T lymphocytes in nu/nu lymph node cells.
W Rudnicka, and
H Długońska, and
P Zelazowski, and
K Szewczyk, and
T Gościcka
August 1972,
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W Rudnicka, and
H Długońska, and
P Zelazowski, and
K Szewczyk, and
T Gościcka
December 1973,
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W Rudnicka, and
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P Zelazowski, and
K Szewczyk, and
T Gościcka
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W Rudnicka, and
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T Gościcka
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W Rudnicka, and
H Długońska, and
P Zelazowski, and
K Szewczyk, and
T Gościcka
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W Rudnicka, and
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P Zelazowski, and
K Szewczyk, and
T Gościcka
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W Rudnicka, and
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T Gościcka
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W Rudnicka, and
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T Gościcka
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W Rudnicka, and
H Długońska, and
P Zelazowski, and
K Szewczyk, and
T Gościcka
January 1971,
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W Rudnicka, and
H Długońska, and
P Zelazowski, and
K Szewczyk, and
T Gościcka
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