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Thirty-four patients with acute gastroduodenal hemorrhage were treated with intravenous Cimetidine. Preliminary endoscopy was done at the onset of bleeding to determine the source of bleeding and to rule out the presence of a brisk arterial bleeding site that would require immediate operation for control. Sixteen of the patients had primary peptic ulcer disease and 18 patients had "stress ulcer" syndrome. The bleeding stopped following Cimetidine administration in 14 of the 16 peptic ulcer patients (88%) and in 13 of 18 stress ulcer patients (72%). There was no subsequent rebleeding. The data suggest that Cimetidine is of value in the immediate nonoperative management of acute gastroduodenal hemorrhage. Further, the availability of Cimetidine for postoperative use may modify the surgical approach to stress ulcer bleeding.
M P Bubrick, and
R E Wetherille, and
G R Onstad, and
R C Andersen, and
C R Hitchcock
October 1982,
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen,
M P Bubrick, and
R E Wetherille, and
G R Onstad, and
R C Andersen, and
C R Hitchcock
January 1987,
Annual review of medicine,
M P Bubrick, and
R E Wetherille, and
G R Onstad, and
R C Andersen, and
C R Hitchcock
January 1984,
Annales chirurgiae et gynaecologiae,
M P Bubrick, and
R E Wetherille, and
G R Onstad, and
R C Andersen, and
C R Hitchcock
May 1956,
American journal of surgery,
M P Bubrick, and
R E Wetherille, and
G R Onstad, and
R C Andersen, and
C R Hitchcock
December 1949,
Journal of the American Medical Association,
M P Bubrick, and
R E Wetherille, and
G R Onstad, and
R C Andersen, and
C R Hitchcock
January 1997,
Khirurgiia,
M P Bubrick, and
R E Wetherille, and
G R Onstad, and
R C Andersen, and
C R Hitchcock
January 1978,
Journal of the Royal College of Surgeons of Edinburgh,
M P Bubrick, and
R E Wetherille, and
G R Onstad, and
R C Andersen, and
C R Hitchcock
February 1977,
Lancet (London, England),
M P Bubrick, and
R E Wetherille, and
G R Onstad, and
R C Andersen, and
C R Hitchcock
January 1968,
Klinicheskaia khirurgiia,
M P Bubrick, and
R E Wetherille, and
G R Onstad, and
R C Andersen, and
C R Hitchcock
February 1992,
Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti,
