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Serum and tissue concentrations of 5-FU and FT-207 were estimated in 26 patients with bladder tumor or prostatic carcinoma after administration of FT-207 suppositories. The 5-FU concentration in bladder tumor was higher than in normal mucosal bladder tissue. The 5-FU concentration of prostatic cancer was almost equal to that of normal prostatic tissue. Relatively higher concentrations of 5-FU were recognized in bladder tumor of a high stage than of a low stage. There were no differences of serum and tissue 5-FU concentration in bladder tumor between patients more than 65 years old and those under 65 years old. No side-effects occurred in any case during suppository administration.
H Kobayashi, and
M Sahashi, and
K Obata
August 1984,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Kobayashi, and
M Sahashi, and
K Obata
October 1987,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Kobayashi, and
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K Obata
April 1984,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Kobayashi, and
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May 1985,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Kobayashi, and
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July 1982,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Kobayashi, and
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January 1985,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Kobayashi, and
M Sahashi, and
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October 1985,
Gan no rinsho. Japan journal of cancer clinics,
H Kobayashi, and
M Sahashi, and
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February 1986,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Kobayashi, and
M Sahashi, and
K Obata
September 1982,
Gan to kagaku ryoho. Cancer & chemotherapy,
H Kobayashi, and
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February 1989,
Gan to kagaku ryoho. Cancer & chemotherapy,
