-transparent.png){kind=logo}
When human blood lymphocytes are cultured in vitro without any intended stimulus, they produce activities in the supernatant resembling lymphokine. This phenomenon was further investigated in the present study, where it has been demonstrated by physicochemical characterization and inhibition experiments that leukocyte migration inhibitory activity in the supernatants is due to leukocyte inhibitory factor (LIF). When T and B lymphocytes were purified by carbonyl iron and SRBC-rosette sedimentation, only B cells produced LIF and leukocyte chemotactic lymphokine(s) in subsequent cultures. B cells elaborated lymphokines without the help of T cells. the need for co-operation of monocytes was also unlikely. T cells were inactive even when reconstituted with monocytes and platelets.
H Arvilommi, and
L Räsänen, and
A Laatikainen, and
E Karhumäki
July 1986,
Journal of periodontal research,
H Arvilommi, and
L Räsänen, and
A Laatikainen, and
E Karhumäki
May 1981,
Infection and immunity,
H Arvilommi, and
L Räsänen, and
A Laatikainen, and
E Karhumäki
January 1992,
Cancer immunology, immunotherapy : CII,
H Arvilommi, and
L Räsänen, and
A Laatikainen, and
E Karhumäki
June 1975,
Annals of the New York Academy of Sciences,
H Arvilommi, and
L Räsänen, and
A Laatikainen, and
E Karhumäki
January 1981,
International archives of allergy and applied immunology,
H Arvilommi, and
L Räsänen, and
A Laatikainen, and
E Karhumäki
January 1988,
Lymphokine research,
H Arvilommi, and
L Räsänen, and
A Laatikainen, and
E Karhumäki
June 1992,
Scandinavian journal of immunology,
H Arvilommi, and
L Räsänen, and
A Laatikainen, and
E Karhumäki
January 1987,
Beitrage zu Infusionstherapie und klinische Ernahrung,
H Arvilommi, and
L Räsänen, and
A Laatikainen, and
E Karhumäki
January 1981,
Developments in biological standardization,
H Arvilommi, and
L Räsänen, and
A Laatikainen, and
E Karhumäki
January 1987,
Clinical and experimental immunology,
