Biomaterial Database

Predicting posttraumatic epilepsy in penetrating head injury. 1986

G H Weiss, and A M Salazar, and S C Vance, and J H Grafman, and B Jabbari

Using data derived from a 15-year follow-up study of 520 veterans surviving penetrating brain wounds received in the Vietnam war, we have developed a predictive formula and tables for posttraumatic epilepsy based on time elapsed postinjury and presence of specific clinical and computed tomographic scan risk factors. Such patients remain at some increased risk for epilepsy even ten to 15 years postinjury, although most can be 95% certain of avoiding epilepsy if they have been seizure free for three years posttrauma. Epilepsy onset latency was independent of any risk factors identified.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D001930	Brain Injuries	Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.	Brain Lacerations,Acute Brain Injuries,Brain Injuries, Acute,Brain Injuries, Focal,Focal Brain Injuries,Injuries, Acute Brain,Injuries, Brain,Acute Brain Injury,Brain Injury,Brain Injury, Acute,Brain Injury, Focal,Brain Laceration,Focal Brain Injury,Injuries, Focal Brain,Injury, Acute Brain,Injury, Brain,Injury, Focal Brain,Laceration, Brain,Lacerations, Brain
D004834	Epilepsy, Post-Traumatic	Recurrent seizures causally related to CRANIOCEREBRAL TRAUMA. Seizure onset may be immediate but is typically delayed for several days after the injury and may not occur for up to two years. The majority of seizures have a focal onset that correlates clinically with the site of brain injury. Cerebral cortex injuries caused by a penetrating foreign object (CRANIOCEREBRAL TRAUMA, PENETRATING) are more likely than closed head injuries (HEAD INJURIES, CLOSED) to be associated with epilepsy. Concussive convulsions are nonepileptic phenomena that occur immediately after head injury and are characterized by tonic and clonic movements. (From Rev Neurol 1998 Feb;26(150):256-261; Sports Med 1998 Feb;25(2):131-6)	Concussive Convulsion,Epilepsy, Traumatic,Impact Seizure,Seizure Disorder, Post-Traumatic,Early Post-Traumatic Seizures,Late Post-Traumatic Seizures,Post-Traumatic Seizure Disorder,Concussive Convulsions,Convulsion, Concussive,Convulsions, Concussive,Disorder, Post-Traumatic Seizure,Disorders, Post-Traumatic Seizure,Early Post Traumatic Seizures,Early Post-Traumatic Seizure,Epilepsies, Post-Traumatic,Epilepsies, Traumatic,Epilepsy, Post Traumatic,Impact Seizures,Late Post Traumatic Seizures,Late Post-Traumatic Seizure,Post Traumatic Seizure Disorder,Post-Traumatic Epilepsies,Post-Traumatic Epilepsy,Post-Traumatic Seizure Disorders,Post-Traumatic Seizure, Early,Post-Traumatic Seizure, Late,Post-Traumatic Seizures, Early,Post-Traumatic Seizures, Late,Seizure Disorder, Post Traumatic,Seizure Disorders, Post-Traumatic,Seizure, Early Post-Traumatic,Seizure, Late Post-Traumatic,Seizures, Early Post-Traumatic,Seizures, Late Post-Traumatic,Traumatic Epilepsies,Traumatic Epilepsy
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012306	Risk	The probability that an event will occur. It encompasses a variety of measures of the probability of a generally unfavorable outcome.	Relative Risk,Relative Risks,Risk, Relative,Risks,Risks, Relative
D014950	Wounds, Penetrating	Wounds caused by objects penetrating the skin.	Penetrating Wound,Penetrating Wounds,Wound, Penetrating