-transparent.png){kind=logo}
High levels of tyrosine protein kinase have been recently detected in the membranes of rat spleen. In the present report the tyrosine protein kinase activity of the 30,000 x g pellet of rat spleen has been solubilized and partially purified by ion exchange and gel permeation chromatography. Two peaks of tyrosine protein kinase of Mr 35,000 (TPK-I) and Mr 40,000 (TPK-II) have been resolved. These kinases were free of the EGF receptor and insulin receptor tyrosine protein kinases. Although TPK-I and TPK-II phosphorylated angiotensin II, casein, histone, tubulin, phosphorylase b, and p36 they differed from each other in preference for the substrates. Both tyrosine protein kinases did not phosphorylate anti-pp60v-src IgG.
M Tokuda, and
N C Khanna, and
A K Arora, and
D M Waisman
March 1988,
European journal of biochemistry,
M Tokuda, and
N C Khanna, and
A K Arora, and
D M Waisman
September 1985,
FEBS letters,
M Tokuda, and
N C Khanna, and
A K Arora, and
D M Waisman
January 1993,
Progress in nucleic acid research and molecular biology,
M Tokuda, and
N C Khanna, and
A K Arora, and
D M Waisman
January 1983,
The Journal of biological chemistry,
M Tokuda, and
N C Khanna, and
A K Arora, and
D M Waisman
November 1990,
European journal of biochemistry,
M Tokuda, and
N C Khanna, and
A K Arora, and
D M Waisman
December 1993,
Molecular reproduction and development,
M Tokuda, and
N C Khanna, and
A K Arora, and
D M Waisman
February 1995,
Analytical biochemistry,
M Tokuda, and
N C Khanna, and
A K Arora, and
D M Waisman
May 1983,
Proceedings of the National Academy of Sciences of the United States of America,
M Tokuda, and
N C Khanna, and
A K Arora, and
D M Waisman
December 1990,
European journal of biochemistry,
M Tokuda, and
N C Khanna, and
A K Arora, and
D M Waisman
September 2001,
Neuroscience letters,
