The influence of a 10 Hz, 0.5 mT (millitesla) alternating magnetic field (rectangular function) on immunologic parameters was investigated. In four chambers, each containing 15 mice, the following electroclimatic conditions existed: conventionally air conditioned laboratory (L), screening of the ambient atmospheric electric fields (F), Faradayscreening plus the above mentioned magnetic field (F + M) and the magnetic field only (M). After 14 days of acclimatizing without magnetic field influence the mice were exposed to the field in the chambers F + M and M for 1, 3, 7 and 21 days, respectively. At the end of the exposure immunological reactions were examined. METHODS Plaquetest (hemolysis in gel) according to Jerne et al. and determination of the hemagglutination titer. The different groups (L, F, F + M and M) were compared using the Student-t test or variance analysis. RESULTS After 7 days of field exposure the plaquecount and the hemagglutination titer (converted into the logarithm of base 2) increased significantly in comparison to the controls (L and F, respectively) in some experiments. In experiments carried out with 3 and 21 days of exposure the same tendency (increase of immunological reaction) was detected.