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Massive rectal bleeding may complicate Crohn's disease at any stage and tends to be persistent. Limited experience gained with this complication supports the use of selective agiography followed by conservative resection as the management of choice. Results of experimental studies suggest that selective infusion of vasopressors may be safely attempted when hemorrhage complicates Crohn's disease in its early stages but is probably too hazardous in cases in which the disease is more advanced.
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