The solid-liquid equilibrium (SLE) in the ternary system 2-keto-L-gulonic acid (HKGA) + L-ascorbic acid (vitamin C) + water was investigated experimentally at temperatures between 276 K and 308 K at ambient pressure, i.e., under conditions that are of particular interest for industrial applications. Phase diagrams with one eutonic point were obtained for all temperatures. The dissociation constant and the solubility constant of vitamin C were determined as a function of temperature. Based on an extended version of the Debye-Hückel theory, a physicochemical model was developed that describes the SLE in the ternary system. The agreement between experimental data and results from the model is excellent.