Balanced Reciprocal Translocation: Multiple Chromosome Rearrangements in an Infertile Female. 2019

Neelam Gupta, and Rupa Dalvi, and Neeraja Koppaka, and Swarna Mandava
Division of Cytogenetics, SRL Diagnostics, Mumbai, Maharashtra, India.

Double reciprocal translocations and triple-balanced reciprocal translocations multiple chromosome rearrangements are very rare events in the phenotypically normal individuals. Chromosome analysis with 500-band resolution was performed and analyzed in an infertile woman. Her karyotype revealed 46,XX, t(1;3) (q44;p11), t(2;14) (q11.2;q13), t(9;11) (p22;p15) pattern in all the metaphases. To the best of our knowledge, this is the first case of triple-balanced reciprocal translocations in an infertile woman.

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