Health related quality of life of dialysis patients in Malaysia: Haemodialysis versus continuous ambulatory peritoneal dialysis. 2019

Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
Department of Community Health, Faculty of Medicine, Pusat Perubatan Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, 56000, Kuala Lumpur, Cheras, Malaysia.

Health related quality of life (HRQOL) is an important predictor of clinical outcomes for End Stage Renal Disease (ESRD) patients and to establish quality adjusted life years (QALYs) for economic evaluation studies. This study aims to measure the health utilities and to identify socio-demographic and clinical factors associated with HRQOL for haemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD) in Malaysia. A total of 141 patients (77 HD and 64 CAPD) from 1 federal and four state hospitals participated in this cross-sectional study. Patients were randomly selected from the National Renal Registry (NRR) using a stratified random sampling. The EQ-5D-3 L questionnaire was used to measure HRQOL. Variables investigated include dialysis modalities, sociodemographic characteristics, co-morbidities and biochemical markers. Utilities are measured on an ordinal scale of 0-1, where 1 indicates full health and 0 indicates death. The mean utility scores were 0.854 ± 0.181 and 0.905 ± 0.124 (p > 0.05) and the mean Visual Analogue Scale (VAS) scores were 76.2 ± 12.90 and 77.1 ± 10.26 (p > 0.05) for HD and CAPD patients respectively. There was a significant difference in problems reported between HD (35.1%) and CAPD (15.6%) on usual activities dimension (p = 0.009). The proportion of patients having problems in the pain/discomfort domain in both modalities was high (34.0%). Haemoglobin (< 10 g/dL) (p = 0.003), number of co-morbidities ≥3 (p = 0.004) and wheelchair-bound status (p < 0.001) were significant predictors of poor HRQOL. The present cross-sectional study shows that CAPD patients have a higher utility index score than HD patients but this was not statistically significant. The utilities index score may be used to calculate QALYs.

UI MeSH Term Description Entries
D007676 Kidney Failure, Chronic The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION. ESRD,End-Stage Renal Disease,Renal Disease, End-Stage,Renal Failure, Chronic,Renal Failure, End-Stage,Chronic Kidney Failure,End-Stage Kidney Disease,Chronic Renal Failure,Disease, End-Stage Kidney,Disease, End-Stage Renal,End Stage Kidney Disease,End Stage Renal Disease,End-Stage Renal Failure,Kidney Disease, End-Stage,Renal Disease, End Stage,Renal Failure, End Stage
D008296 Malaysia A parliamentary democracy with a constitutional monarch in southeast Asia, consisting of 11 states (West Malaysia) on the Malay Peninsula and two states (East Malaysia) on the island of BORNEO. It is also called the Federation of Malaysia. Its capital is Kuala Lumpur. Before 1963 it was the Union of Malaya. It reorganized in 1948 as the Federation of Malaya, becoming independent from British Malaya in 1957 and becoming Malaysia in 1963 as a federation of Malaya, Sabah, Sarawak, and Singapore (which seceded in 1965). The form Malay- probably derives from the Tamil malay, mountain, with reference to its geography. (From Webster's New Geographical Dictionary, 1988, p715 & Room, Brewer's Dictionary of Names, 1992, p329) Federation of Malaya,Malay Federation,Malay Peninsula,Malaya,Malaya Federation,Sabah,Sarawak
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010147 Pain Measurement Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies. Analgesia Tests,Analogue Pain Scale,Formalin Test,McGill Pain Questionnaire,Nociception Tests,Pain Assessment,Pain Intensity,Pain Severity,Tourniquet Pain Test,Visual Analogue Pain Scale,Analog Pain Scale,Assessment, Pain,McGill Pain Scale,Visual Analog Pain Scale,Analgesia Test,Analog Pain Scales,Analogue Pain Scales,Formalin Tests,Intensity, Pain,Measurement, Pain,Nociception Test,Pain Assessments,Pain Intensities,Pain Measurements,Pain Questionnaire, McGill,Pain Scale, Analog,Pain Scale, Analogue,Pain Scale, McGill,Pain Severities,Pain Test, Tourniquet,Questionnaire, McGill Pain,Scale, Analog Pain,Scale, Analogue Pain,Scale, McGill Pain,Severity, Pain,Test, Analgesia,Test, Formalin,Test, Nociception,Test, Tourniquet Pain,Tests, Nociception,Tourniquet Pain Tests
D010531 Peritoneal Dialysis, Continuous Ambulatory Portable peritoneal dialysis using the continuous (24 hours a day, 7 days a week) presence of peritoneal dialysis solution in the peritoneal cavity except for periods of drainage and instillation of fresh solution. CAPD,Continuous Ambulatory Peritoneal Dialysis
D011788 Quality of Life A generic concept reflecting concern with the modification and enhancement of life attributes, e.g., physical, political, moral, social environment as well as health and disease. HRQOL,Health-Related Quality Of Life,Life Quality,Health Related Quality Of Life
D003430 Cross-Sectional Studies Studies in which the presence or absence of disease or other health-related variables are determined in each member of the study population or in a representative sample at one particular time. This contrasts with LONGITUDINAL STUDIES which are followed over a period of time. Disease Frequency Surveys,Prevalence Studies,Analysis, Cross-Sectional,Cross Sectional Analysis,Cross-Sectional Survey,Surveys, Disease Frequency,Analyses, Cross Sectional,Analyses, Cross-Sectional,Analysis, Cross Sectional,Cross Sectional Analyses,Cross Sectional Studies,Cross Sectional Survey,Cross-Sectional Analyses,Cross-Sectional Analysis,Cross-Sectional Study,Cross-Sectional Surveys,Disease Frequency Survey,Prevalence Study,Studies, Cross-Sectional,Studies, Prevalence,Study, Cross-Sectional,Study, Prevalence,Survey, Cross-Sectional,Survey, Disease Frequency,Surveys, Cross-Sectional
D005260 Female Females
D006304 Health Status The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures. General Health,General Health Level,General Health Status,Level of Health,Overall Health,Overall Health Status,General Health Levels,Health Level,Health Level, General,Health Levels,Health Status, General,Health Status, Overall,Health, General,Health, Overall,Level, General Health,Levels, General Health,Status, General Health,Status, Health,Status, Overall Health

Related Publications

Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
June 2000, Journal of advanced nursing,
Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
June 2018, PharmacoEconomics - open,
Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
November 1986, Clinics in endocrinology and metabolism,
Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
December 2003, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
January 2007, Revista medica del Instituto Mexicano del Seguro Social,
Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
January 1991, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
February 2005, Nephrology (Carlton, Vic.),
Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
October 2008, Nephrology (Carlton, Vic.),
Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
January 2001, Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
Naren Kumar Surendra, and Mohd Rizal Abdul Manaf, and Lai Seong Hooi, and Sunita Bavanandan, and Fariz Safhan Mohamad Nor, and Shahnaz Shah Firdaus Khan, and Loke Meng Ong, and Abdul Halim Abdul Gafor
October 2010, Hemodialysis international. International Symposium on Home Hemodialysis,
Copied contents to your clipboard!