BIOMAT Database Logo BIOMAT Database Logo

Mepolizumab in patients with eosinophilic granulomatosis with polyangiitis. 2019

Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Tareev Clinic of Internal Diseases, Sechenov First Moscow State Medical University, Moscow, Russia. Electronic address: clinpharm@mtu-net.ru.

UI MeSH Term Description Entries
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014890 Granulomatosis with Polyangiitis A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and KIDNEYS. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against MYELOBLASTIN. Granulomatosis, Wegener's,Wegener Granulomatosis,Wegener's Granulomatosis,Granulomatosis with Polyangiitides,Granulomatosis, Wegener,Polyangiitides, Granulomatosis with,Polyangiitis, Granulomatosis with,with Polyangiitides, Granulomatosis,with Polyangiitis, Granulomatosis
D015267 Churg-Strauss Syndrome Widespread necrotizing angiitis with granulomas. Pulmonary involvement is frequent. Asthma or other respiratory infection may precede evidence of vasculitis. Eosinophilia and lung involvement differentiate this disease from POLYARTERITIS NODOSA. Allergic Angiitis,Allergic Granulomatous Angiitis,Angiitis, Allergic Granulomatous,EGPA Disorder,Eosinophilic Granulomatosis with Polyangiitis,Vasculitis, Churg-Strauss,Allergic Angiitis and Granulomatosis,Allergic Granulomatosis,Allergic Granulomatous and Angiitis,Eosinophilic Granulomatous Vasculitis,Granulomatous Allergic Angiitis,Allergic Angiitides,Allergic Angiitides, Granulomatous,Allergic Angiitis, Granulomatous,Allergic Granulomatoses,Allergic Granulomatous Angiitides,Angiitides, Allergic,Angiitides, Allergic Granulomatous,Angiitides, Granulomatous Allergic,Angiitis, Allergic,Angiitis, Granulomatous Allergic,Churg Strauss Syndrome,Churg-Strauss Vasculitis,Disorder, EGPA,Disorders, EGPA,EGPA Disorders,Granulomatoses, Allergic,Granulomatosis, Allergic,Granulomatous Allergic Angiitides,Granulomatous Angiitides, Allergic,Granulomatous Angiitis, Allergic,Granulomatous Vasculitides, Eosinophilic,Granulomatous Vasculitis, Eosinophilic,Syndrome, Churg-Strauss,Vasculitides, Eosinophilic Granulomatous,Vasculitis, Churg Strauss,Vasculitis, Eosinophilic Granulomatous
D015848 Interleukin-5 A cytokine that promotes differentiation and activation of EOSINOPHILS. It also triggers activated B-LYMPHOCYTES to differentiate into IMMUNOGLOBULIN-secreting cells. B-Cell Growth Factor-II,Eosinophil Differentiation Factor,IL-5,T-Cell Replacing Factor,BCGF-II,Differentiation Factor, Eosinophil,IL5,T-Cell-Replacing Factor,B Cell Growth Factor II,Interleukin 5,Replacing Factor, T-Cell,T Cell Replacing Factor
D061067 Antibodies, Monoclonal, Humanized Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab. Antibodies, Humanized,Humanized Antibodies

Related Publications

Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Vasculitis: Mepolizumab for eosinophilic granulomatosis with polyangiitis.
September 2017, Nature reviews. Rheumatology,
Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Mepolizumab to treat eosinophilic granulomatosis with polyangiitis.
February 2024, Medicina clinica,
Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Mepolizumab Treatment of Pediatric Eosinophilic Granulomatosis With Polyangiitis.
April 2018, JAMA dermatology,
Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis.
May 2017, The New England journal of medicine,
Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Benralizumab versus Mepolizumab for Eosinophilic Granulomatosis with Polyangiitis.
May 2024, The New England journal of medicine,
Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Benralizumab versus Mepolizumab for Eosinophilic Granulomatosis with Polyangiitis.
March 2024, The New England journal of medicine,
Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Safety and Efficacy of Mepolizumab in Patients with Eosinophilic Granulomatosis with Polyangiitis.
January 2019, Pulmonary medicine,
Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Mepolizumab and Eosinophilic Pleural Effusion in Patient With Eosinophilic Granulomatosis With Polyangiitis.
July 2023, Archivos de bronconeumologia,
Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Mepolizumab for the treatment of eosinophilic granulomatosis with polyangiitis.
February 2018, Drugs of today (Barcelona, Spain : 1998),
Sergey Moiseev, and Eugenia Zagvozdkina, and Viktoria Kazarina, and Nikolai Bulanov, and Pavel Novikov
Benralizumab versus Mepolizumab for Eosinophilic Granulomatosis with Polyangiitis. Reply.
May 2024, The New England journal of medicine,
Copied contents to your clipboard!