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Profile of Pediatric Scrub Typhus in Odisha, India. 2019

Madhusmita Bal, and Mahesh Prasad Mohanta, and Suneeta Sahu, and Bhagirathi Dwibedi, and Sanghamitra Pati, and Manoranjan Ranjit
ICMR-Regional Medical Research Centre, Bhubaneswar, Odisha, India.

To investigate the distribution and clinical profile of scrub typhus infection among children with acute febrile illness in Odisha. Children (<15 y) presenting with acute fever (>5 days) in 4 agro-climatic zones from June to November 2017 were evaluated. Patients were screened for malaria, leptospira, dengue, typhoid and scrub typhus. Scrub typhus was confirmed by IgM ELISA and PCR. Out of 413 cases examined, 48.7% were positive for scrub typhus, and 5.5% of them developed systemic complications. Eschar was found in 17.9% of cases. Five days treatment of Doxycycline and/or Azithromycin was clinically effective against scrub typhus. Our study highlights that scrub typhus is one of the causes of high morbidity in children during rainy months in Odisha.

UI MeSH Term Description Entries
D007194 India A country in southern Asia, bordering the Arabian Sea and the Bay of Bengal, between Burma and Pakistan. The capitol is New Delhi. Republic of India
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008297 Male Males
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D005260 Female Females
D005334 Fever An abnormal elevation of body temperature, usually as a result of a pathologic process. Pyrexia,Fevers,Pyrexias
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000071072 Acute Febrile Encephalopathy Acute onset of fever accompanied by seizures, cerebral inflammation and a change in mental status (e.g., confusion, disorientation, and coma). Acute Encephalitis Syndrome,Encephalopathy, Febrile,Acute Encephalitis Syndromes,Acute Febrile Encephalopathies,Encephalopathies, Acute Febrile,Encephalopathies, Febrile,Encephalopathy, Acute Febrile,Febrile Encephalopathies,Febrile Encephalopathies, Acute,Febrile Encephalopathy

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