-transparent.png){kind=logo}
Twenty-five children with generalized histiocytosis X were treated with a combination of cyclophosphamide, vinblastine, and prednisone: 8 patients experienced complete response, 8 partial response, 2 imporvement, and 7 no response. Response rates for children over 1 year of age were higher than those reported for single agents. Twelve children are now off therapy with no evidence of disease for 10--50 months. Very poor response rates and high toxicity were seen in children less than 1 year of age. The two infants who eventually achieved CR did so by other therapies. Further trials in combination chemotherapy must weight possible long-term effects of such therapy against the prospect of more rapid disease control.
D M Komp, and
T J Vietti, and
D H Berry, and
K A Starling, and
M E Haggard, and
S L George
March 1987,
Hematology/oncology clinics of North America,
D M Komp, and
T J Vietti, and
D H Berry, and
K A Starling, and
M E Haggard, and
S L George
January 1979,
Acta haematologica,
D M Komp, and
T J Vietti, and
D H Berry, and
K A Starling, and
M E Haggard, and
S L George
June 1988,
Journal of the Royal Society of Medicine,
D M Komp, and
T J Vietti, and
D H Berry, and
K A Starling, and
M E Haggard, and
S L George
February 1989,
Journal of the Royal Society of Medicine,
D M Komp, and
T J Vietti, and
D H Berry, and
K A Starling, and
M E Haggard, and
S L George
January 1994,
Journal of Tongji Medical University = Tong ji yi ke da xue xue bao,
D M Komp, and
T J Vietti, and
D H Berry, and
K A Starling, and
M E Haggard, and
S L George
September 1976,
Cancer,
D M Komp, and
T J Vietti, and
D H Berry, and
K A Starling, and
M E Haggard, and
S L George
April 1983,
Pediatriia,
D M Komp, and
T J Vietti, and
D H Berry, and
K A Starling, and
M E Haggard, and
S L George
January 1983,
Acta radiologica. Oncology,
D M Komp, and
T J Vietti, and
D H Berry, and
K A Starling, and
M E Haggard, and
S L George
January 1978,
Medical and pediatric oncology,
D M Komp, and
T J Vietti, and
D H Berry, and
K A Starling, and
M E Haggard, and
S L George
October 1984,
Orvosi hetilap,
