Impact of Culture Conditions on Neutral Lipid Production by Oleaginous Yeast. 2019

Irene Fakankun, and Maryam Mirzaei, and David B Levin
Department of Biosystems Engineering, University of Manitoba, Winnipeg, MB, Canada.

Oleaginous yeasts have the ability to accumulate and store triacylglycerides (TAGs) to more than 20% of their cell mass. Oleaginous yeasts have advantages over oil seed plants and microalgae because they grow much faster (doubling time is usually less than an hour), accumulate cell mass to much higher densities, and are less affected by seasonal or weather conditions. The TAGs synthesized by oleaginous yeasts are often rich in polyunsaturated fatty acids and can be used either for biodiesel production or as edible oils. "Red" yeasts are oleaginous yeasts that can synthesize and accumulate high concentrations of TAGs. Many factors affect the growth of red yeasts and subsequent yields of TAGs. These factors include carbon and nitrogen sources, their concentrations, the C/N ratio, temperature, pH, aeration rate, mineral elements, inorganic salts, and inhibitors. The effect of each factor varies with the yeast strain and its growth phase. Rhodosporidium diobovatum is a "red" yeast that can utilize low-cost substrates, such as waste glycerol derived from biodiesel production as a carbon source, and can synthesize and accumulate high concentrations of both TAGs and carotenoids.

UI MeSH Term Description Entries
D007218 Industrial Microbiology The study, utilization, and manipulation of those microorganisms capable of economically producing desirable substances or changes in substances, and the control of undesirable microorganisms. Microbiology, Industrial
D008055 Lipids A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed) Lipid
D009584 Nitrogen An element with the atomic symbol N, atomic number 7, and atomic weight [14.00643; 14.00728]. Nitrogen exists as a diatomic gas and makes up about 78% of the earth's atmosphere by volume. It is a constituent of proteins and nucleic acids and found in all living cells.
D002244 Carbon A nonmetallic element with atomic symbol C, atomic number 6, and atomic weight [12.0096; 12.0116]. It may occur as several different allotropes including DIAMOND; CHARCOAL; and GRAPHITE; and as SOOT from incompletely burned fuel. Carbon-12,Vitreous Carbon,Carbon 12,Carbon, Vitreous
D002338 Carotenoids The general name for a group of fat-soluble pigments found in green, yellow, and leafy vegetables, and yellow fruits. They are aliphatic hydrocarbons containing 4 terpene subunits. Carotenes,Carotenoid,Tetraterpene Derivatives,Tetraterpenes,Carotene,Derivatives, Tetraterpene
D006863 Hydrogen-Ion Concentration The normality of a solution with respect to HYDROGEN ions; H+. It is related to acidity measurements in most cases by pH pH,Concentration, Hydrogen-Ion,Concentrations, Hydrogen-Ion,Hydrogen Ion Concentration,Hydrogen-Ion Concentrations
D013696 Temperature The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms. Temperatures
D014280 Triglycerides An ester formed from GLYCEROL and three fatty acid groups. Triacylglycerol,Triacylglycerols,Triglyceride
D015003 Yeasts A general term for single-celled rounded fungi that reproduce by budding. Brewers' and bakers' yeasts are SACCHAROMYCES CEREVISIAE; therapeutic dried yeast is YEAST, DRIED. Yeast
D050155 Lipogenesis De novo fat synthesis in the body. This includes the synthetic processes of FATTY ACIDS and subsequent TRIGLYCERIDES in the LIVER and the ADIPOSE TISSUE. Lipogenesis is regulated by numerous factors, including nutritional, hormonal, and genetic elements. Lipogeneses

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