Biomaterial Database

Comparison of recovery after halothane or alfentanil anaesthesia for minor surgery. 1987

E Moss, and I Hindmarch, and A J Pain, and R S Edmondson

Department of Anaesthetics, Leeds General Infirmary.

Recovery after anaesthesia was assessed using the Maddox Wing Test (MW), Critical Flicker Fusion Threshold (CFF), Choice Reaction Time (CRT), Line Analogue Rating Scales (LARS), a Tracking Test and a test of Semantic Memory in 44 patients who had undergone minor gynaecological surgery. The patients were allocated randomly to one of two groups and received either methohexitone, nitrous oxide, oxygen and halothane or methohexitone, alfentanil, nitrous oxide and oxygen. Immediate recovery was more rapid in the alfentanil group (P less than 0.01), but apnoea (P less than 0.05) and hiccups (P less than 0.05) were more common. Except for the CFF test, which showed the alfentanil patients to be less sedated than the halothane patients on the morning after anaesthesia (P less than 0.05), the results of the tests were similar in both groups and showed, initially, substantial impairment of psychomotor functions which gradually returned to baseline values. This comparison with halothane anaesthesia indicates that a technique using methohexitone and alfentanil is suitable for day-case surgery.

UI	MeSH Term	Description	Entries
D007431	Intraoperative Complications	Complications that affect patients during surgery. They may or may not be associated with the disease for which the surgery is done, or within the same surgical procedure.	Peroperative Complications,Surgical Injuries,Complication, Intraoperative,Complication, Peroperative,Injuries, Surgical,Complications, Intraoperative,Complications, Peroperative,Injury, Surgical,Intraoperative Complication,Peroperative Complication,Surgical Injury
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011183	Postoperative Complications	Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.	Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D011184	Postoperative Period	The period following a surgical operation.	Period, Postoperative,Periods, Postoperative,Postoperative Periods
D005260	Female		Females
D005283	Fentanyl	A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)	Phentanyl,Duragesic,Durogesic,Fentanest,Fentanyl Citrate,Fentora,R-4263,Sublimaze,Transmucosal Oral Fentanyl Citrate,R 4263,R4263
D006221	Halothane	A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. NITROUS OXIDE is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)	1,1,1-Trifluoro-2-Chloro-2-Bromoethane,Fluothane,Ftorotan,Narcotan
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly