Identification and characterization of novel genotypes of psittacine beak and feather disease virus from budgerigar in China. 2019

Jingjiao Ma, and Ye Tian, and Min Zhang, and Weili Wang, and Yujie Li, and Fulin Tian, and Yuqiang Cheng, and Yaxian Yan, and Jianhe Sun
Shanghai Key Laboratory of Veterinary Biotechnology, Key Laboratory of Urban Agriculture (South), Ministry of Agriculture, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.

Psittacine beak and feather disease (PBFD) is a common disease in psittacine bird that caused by beak and feather disease virus (BFDV). BFDV is widely spread and threatening psittacine birds worldwide. However, the BFDV infection in China remains largely unknown. In this study, a surveillance study of BFDV was conducted in three budgerigar breeding facilities, which showed that 66.6% of collected faeces samples were positive for BFDV. Full genomes of nine BFDV circulating in the three budgerigar breeding facilities (three for each facility) were determined and analysed. The full genomes shared 75.9% to 87.5% identity with the known genotype BFDV. Phylogenetic analysis of the full genome indicated that the BFDV circulating in China formed a separated group, and the nine isolates fell into three subgroups, suggesting that different unique BFDV genotypes are circulating in China. Notably, the Cap genes of three strains (SD3, SD5 and SD9) showed low identity (67.9% to 70%) to all the known genotypes of BFDV. Phylogenetic analysis showed that these three Cap genes formed a unique lineage that is different from all known genotypes, which suggested that the SD3, SD5 and SD9 strains identified in this study belong to a novel genotype that has not been reported. However, the origin of this genotype remains unclear. All the data indicated that the different unique genotypes of BFDV are co-circulating in China, and active surveillance of BFDV is warranted.

UI MeSH Term Description Entries
D010802 Phylogeny The relationships of groups of organisms as reflected by their genetic makeup. Community Phylogenetics,Molecular Phylogenetics,Phylogenetic Analyses,Phylogenetic Analysis,Phylogenetic Clustering,Phylogenetic Comparative Analysis,Phylogenetic Comparative Methods,Phylogenetic Distance,Phylogenetic Generalized Least Squares,Phylogenetic Groups,Phylogenetic Incongruence,Phylogenetic Inference,Phylogenetic Networks,Phylogenetic Reconstruction,Phylogenetic Relatedness,Phylogenetic Relationships,Phylogenetic Signal,Phylogenetic Structure,Phylogenetic Tree,Phylogenetic Trees,Phylogenomics,Analyse, Phylogenetic,Analysis, Phylogenetic,Analysis, Phylogenetic Comparative,Clustering, Phylogenetic,Community Phylogenetic,Comparative Analysis, Phylogenetic,Comparative Method, Phylogenetic,Distance, Phylogenetic,Group, Phylogenetic,Incongruence, Phylogenetic,Inference, Phylogenetic,Method, Phylogenetic Comparative,Molecular Phylogenetic,Network, Phylogenetic,Phylogenetic Analyse,Phylogenetic Clusterings,Phylogenetic Comparative Analyses,Phylogenetic Comparative Method,Phylogenetic Distances,Phylogenetic Group,Phylogenetic Incongruences,Phylogenetic Inferences,Phylogenetic Network,Phylogenetic Reconstructions,Phylogenetic Relatednesses,Phylogenetic Relationship,Phylogenetic Signals,Phylogenetic Structures,Phylogenetic, Community,Phylogenetic, Molecular,Phylogenies,Phylogenomic,Reconstruction, Phylogenetic,Relatedness, Phylogenetic,Relationship, Phylogenetic,Signal, Phylogenetic,Structure, Phylogenetic,Tree, Phylogenetic
D001947 Breeding The production of offspring by selective mating or HYBRIDIZATION, GENETIC in animals or plants. Breedings
D002681 China A country spanning from central Asia to the Pacific Ocean. Inner Mongolia,Manchuria,People's Republic of China,Sinkiang,Mainland China
D005241 Feathers Flat keratinous structures found on the skin surface of birds. Feathers are made partly of a hollow shaft fringed with barbs. They constitute the plumage. Feather
D005838 Genotype The genetic constitution of the individual, comprising the ALLELES present at each GENETIC LOCUS. Genogroup,Genogroups,Genotypes
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001502 Beak In some animals, the jaws together with their horny covering. The beak usually refers to the bill of birds in which the whole varies greatly in form according of the food and habits of the bird. While the beak refers most commonly to birds, the anatomical counterpart is found also in the turtle, squid, and octopus. (From Webster, 3d ed & Storer, et al., General Zoology, 6th ed, p491, 755) Bill, Avian,Avian Bill,Avian Bills,Beaks,Bills, Avian
D001715 Bird Diseases Diseases of birds not considered poultry, therefore usually found in zoos, parks, and the wild. The concept is differentiated from POULTRY DISEASES which is for birds raised as a source of meat or eggs for human consumption, and usually found in barnyards, hatcheries, etc. Avian Diseases,Avian Disease,Bird Disease,Disease, Avian,Disease, Bird,Diseases, Avian,Diseases, Bird
D016679 Genome, Viral The complete genetic complement contained in a DNA or RNA molecule in a virus. Viral Genome,Genomes, Viral,Viral Genomes
D046408 Melopsittacus A genus, commonly called budgerigars, in the family PSITTACIDAE. In the United States they are considered one of the five species of PARAKEETS. Budgerigars,Budgerigar

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