-transparent.png){kind=logo}
Nucleoside Analogs with Antiviral Activity against Yellow Fever Virus. 2019
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.
Yellow fever virus (YFV) is a human Flavivirus reemerging in parts of the world. While a vaccine is available, large outbreaks have recently occurred in Brazil and certain African countries. Development of an effective antiviral against YFV is crucial, as there is no available effective drug against YFV. We have identified several novel nucleoside analogs with potent antiviral activity against YFV with 50% effective concentration (EC50) values between 0.25 and 1 μM with selectivity indices over 100 in culture.
Related Publications
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
June 1976,
Biochemical pharmacology,
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
September 2023,
PNAS nexus,
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
January 2021,
Chemistry of heterocyclic compounds,
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
March 2017,
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie,
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
October 2004,
Antimicrobial agents and chemotherapy,
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
December 2022,
Antiviral research,
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
January 1987,
Molekuliarnaia genetika, mikrobiologiia i virusologiia,
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
March 2011,
Interdisciplinary sciences, computational life sciences,
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
December 2022,
mSphere,
Keivan Zandi, and
Franck Amblard, and
Sarah Amichai, and
Leda Bassit, and
Sijia Tao, and
Yong Jiang, and
Longhu Zhou, and
Olivia Ollinger Russell, and
Seema Mengshetti, and
Raymond F Schinazi
May 2004,
Mini reviews in medicinal chemistry,
