[Animal experiment studies of high frequency jet ventilation with a newly developed pneumatically controlled respirator]. 1987

U Klein, and D Claussen, and H Schubert, and M Zieger
Klinik für Anästhesiologie und Intensivtherapie, Bereiches Medizin Friedrich-Schiller-Universität Jena/DDR.

The effects of high frequency jet ventilation (HFJV) were investigated in 12 mongrel dogs with normal lungs. A newly developed HFJV device with purely pneumatic regulation was used. In order to evaluate several ventilatory parameters, respiratory rate, breathing time quotient and jet emission pressure were varied. Thus, important ventilatory, hemodynamic and calculated values were recorded. Accordingly, HFJV is possible with the tested device under clinical conditions in the frequency range between 80 and 300/min, with a breathing time ratio of 1:21 to 1:1 and a driving pressure up to 0.4 MPa with an oxygen concentration of FiO2 = 0.21 to 1.0. Before clinical use, however, investigations on the damaged lung of the dog are necessary.

UI MeSH Term Description Entries
D010100 Oxygen An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. Dioxygen,Oxygen-16,Oxygen 16
D011659 Pulmonary Gas Exchange The exchange of OXYGEN and CARBON DIOXIDE between alveolar air and pulmonary capillary blood that occurs across the BLOOD-AIR BARRIER. Exchange, Pulmonary Gas,Gas Exchange, Pulmonary
D002245 Carbon Dioxide A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D006611 High-Frequency Jet Ventilation Respiratory support system used primarily with rates of about 100 to 200/min with volumes of from about one to three times predicted anatomic dead space. Used to treat respiratory failure and maintain ventilation under severe circumstances. Ventilation, High Frequency Jet,High Frequency Jet Ventilation,High-Frequency Jet Ventilations,Jet Ventilation, High-Frequency,Jet Ventilations, High-Frequency,Ventilation, High-Frequency Jet,Ventilations, High-Frequency Jet
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

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