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The pharmacological potential of nanotechnology, especially in drug delivery and bioengineering, has developed rapidly in recent decades. Ion channels, which are easily targeted by external agents, such as nanomaterials (NMs) and synthetic drugs, due to their unique structures, have attracted increasing attention in the fields of nanotechnology and pharmacology for the treatment of ion channel-related diseases. NMs have significant effects on ion channels, and these effects are manifested in many ways, including changes in ion currents, kinetic characteristics and channel distribution. Subsequently, intracellular ion homeostasis, signalling pathways, and intracellular ion stores are affected, leading to the initiation of a range of biological processes. However, the effect of the interactions of NMs with ion channels is an interesting topic that remains obscure. In this review, we have summarized the recent research progress on the direct and indirect interactions between NMs and ion channels and discussed the related molecular mechanisms, which are crucial to the further development of ion channel-related nanotechnological applications.
Suhan Yin, and
Jia Liu, and
Yiyuan Kang, and
Yuqing Lin, and
Dongjian Li, and
Longquan Shao
July 1997,
The Biochemical journal,
Suhan Yin, and
Jia Liu, and
Yiyuan Kang, and
Yuqing Lin, and
Dongjian Li, and
Longquan Shao
December 2019,
Channels (Austin, Tex.),
Suhan Yin, and
Jia Liu, and
Yiyuan Kang, and
Yuqing Lin, and
Dongjian Li, and
Longquan Shao
April 1993,
Trends in neurosciences,
Suhan Yin, and
Jia Liu, and
Yiyuan Kang, and
Yuqing Lin, and
Dongjian Li, and
Longquan Shao
May 1992,
Biophysical journal,
Suhan Yin, and
Jia Liu, and
Yiyuan Kang, and
Yuqing Lin, and
Dongjian Li, and
Longquan Shao
February 2014,
Biochimica et biophysica acta,
Suhan Yin, and
Jia Liu, and
Yiyuan Kang, and
Yuqing Lin, and
Dongjian Li, and
Longquan Shao
September 1994,
Environmental health perspectives,
Suhan Yin, and
Jia Liu, and
Yiyuan Kang, and
Yuqing Lin, and
Dongjian Li, and
Longquan Shao
January 2000,
Acta biochimica Polonica,
Suhan Yin, and
Jia Liu, and
Yiyuan Kang, and
Yuqing Lin, and
Dongjian Li, and
Longquan Shao
January 2018,
Methods in enzymology,
Suhan Yin, and
Jia Liu, and
Yiyuan Kang, and
Yuqing Lin, and
Dongjian Li, and
Longquan Shao
January 2023,
Handbook of experimental pharmacology,
Suhan Yin, and
Jia Liu, and
Yiyuan Kang, and
Yuqing Lin, and
Dongjian Li, and
Longquan Shao
October 2004,
Progress in biophysics and molecular biology,
