BIOMAT Database Logo BIOMAT Database Logo

Generalized papular pruritic eruption in African patients with human immunodeficiency virus infection. 1987

R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Project SIDA, Ministry of Public Health, Kinshasa, Zaïre.

Of 284 patients hospitalized with HIV infection, 52 (18%) presented with a generalized pruritic papular eruption. No significant association between this eruption and other HIV manifestations or any opportunistic infection was found. Fifty-three of 61 (87%) consecutive African patients referred for a generalized papular pruritic eruption of unknown etiology of at least 1 month's duration were HIV seropositive, including 15 (65%) of 23 in good general condition. Thirty-seven (95%) of 38 patients with this eruption and severe weight loss (greater than 10% of normal body weight) were seropositive. The initial skin lesions were small, firm, intensely pruritic papules which released a small drop of clear fluid when scratched. Scratched papules became later hyperpigmented macules. Lesions were symmetrically distributed over the body and were most frequently found on the extensor surfaces of the arm, the dorsal surface of the hands, the inferior part of the legs, the ankles and the dorsum of the feet. Histologic examination showed a non-specific inflammatory reaction. Thirty-three (51%) patients reported that the skin eruption was their initial disease manifestation. In African patients, the presence of an unexplained generalized pruritic papular eruption is highly indicative of HIV infection.

UI MeSH Term Description Entries
D008297 Male Males
D011537 Pruritus An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief. Itching,Pruritis
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000163 Acquired Immunodeficiency Syndrome An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993. AIDS,Immunodeficiency Syndrome, Acquired,Immunologic Deficiency Syndrome, Acquired,Acquired Immune Deficiency Syndrome,Acquired Immuno-Deficiency Syndrome,Acquired Immuno Deficiency Syndrome,Acquired Immuno-Deficiency Syndromes,Acquired Immunodeficiency Syndromes,Immuno-Deficiency Syndrome, Acquired,Immuno-Deficiency Syndromes, Acquired,Immunodeficiency Syndromes, Acquired,Syndrome, Acquired Immuno-Deficiency,Syndrome, Acquired Immunodeficiency,Syndromes, Acquired Immuno-Deficiency,Syndromes, Acquired Immunodeficiency
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000349 Africa The continent south of EUROPE, east of the ATLANTIC OCEAN and west of the INDIAN OCEAN.
D012871 Skin Diseases Diseases involving the DERMIS or EPIDERMIS. Dermatoses,Skin and Subcutaneous Tissue Disorders,Dermatosis,Skin Disease

Related Publications

R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Papular pruritic eruption with human immunodeficiency virus infection.
November 1991, International journal of dermatology,
R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Factors associated with pruritic papular eruption of human immunodeficiency virus infection in the antiretroviral therapy era.
April 2014, The British journal of dermatology,
R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Pruritic, pink, papular eruption. Generalized granuloma annulare (GA).
August 1987, Archives of dermatology,
R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Papular pruritic eruption of Demodex folliculitis in patients with acquired immunodeficiency syndrome.
August 1989, Journal of the American Academy of Dermatology,
R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Pruritic papular eruption of the acquired immunodeficiency syndrome.
May 1994, Acta dermato-venereologica,
R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Pruritic papular eruption and eosinophilic folliculitis associated with human immunodeficiency virus (HIV) infection: a histopathological and immunohistochemical comparative study.
August 2012, Journal of the American Academy of Dermatology,
R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Pruritic eosinophilic papular eruption revealing HIV infection.
January 2002, European journal of dermatology : EJD,
R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Antihistamines are superior to topical steroids in managing human immunodeficiency virus (HIV)-associated papular pruritic eruption.
January 2010, International journal of dermatology,
R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Etiology of pruritic papular eruption with HIV infection in Uganda.
December 2004, JAMA,
R Colebunders, and J M Mann, and H Francis, and K Bila, and L Izaley, and N Kakonde, and A F Hood, and T C Quinn, and P Gigase, and E Van Marck
Pruritic papular eruption in HIV.
October 2006, Dermatologic clinics,
Copied contents to your clipboard!