Biomaterial Database

[Sensitivity of the respiratory regulatory apparatus to CO2 under simulated space flight conditions]. 1988

L R Iseev, and A Ia Mednykh, and V E Vorob'ev, and V R Abdrakhmanov

Using the rebreathing method, CO2 sensitivity of the respiration regulation system was investigated during a year-long enclosure study and head-down tilt tests of varying duration (up to 120 days). During the exposures CO2 and H+ were built up in the body. In the course of the enclosure study CO2 sensitivity was reduced. During bed rest experiments this parameter changed differently: it increased on day 7 and significantly decreased on days 55 to 100. These findings show that respiration regulation may vary markedly and indicate that it is worthwhile to carry out similar investigations in an actual space flight.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011187	Posture	The position or physical attitude of the body.	Postures
D012119	Respiration	The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (	Breathing
D012129	Respiratory Function Tests	Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc.	Lung Function Tests,Pulmonary Function Tests,Function Test, Pulmonary,Function Tests, Pulmonary,Pulmonary Function Test,Test, Pulmonary Function,Tests, Pulmonary Function,Function Test, Lung,Function Test, Respiratory,Function Tests, Lung,Function Tests, Respiratory,Lung Function Test,Respiratory Function Test,Test, Lung Function,Test, Respiratory Function,Tests, Lung Function,Tests, Respiratory Function
D002245	Carbon Dioxide	A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.	Carbonic Anhydride,Anhydride, Carbonic,Dioxide, Carbon
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006935	Hypercapnia	A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001273	Atmosphere Exposure Chambers	Experimental devices used in inhalation studies in which a person or animal is either partially or completely immersed in a chemically controlled atmosphere.	Atmosphere Exposure Chamber,Chamber, Atmosphere Exposure,Chambers, Atmosphere Exposure,Exposure Chamber, Atmosphere,Exposure Chambers, Atmosphere