Morphological and electrophysiological characteristics of the commissural system in the superior colliculi for control of eye movements. 2019

Mayu Takahashi
Department of Systems Neurophysiology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address: takahashi.phy1@tmd.ac.jp.

Commissural connections between the superior colliculi (SCs) were well known anatomically, and assumed to be only inhibitory in relation to visual inputs. However, by recording intracellular potentials, we revealed that a strong monosynaptic excitatory commissural connection exists between the rostral SCs of the cat. Commissural excitation existed between the medial-medial or lateral-lateral parts of both SCs, while commissural inhibition existed between the medial SC on one side and the lateral SC on the opposite side. These commissural excitation and inhibition were also confirmed morphologically with the double-labeling method of HRP-conjugated gold particle and GABA. Similarity of the topography of commissural inhibition between the SC system and the vestibuloocular system supported the conclusion that the saccadic eye movement system uses the same semicircular canal coordinate as the vestibuloocular system. The commissural excitation may help to maintain Listing's law in saccadic eye movements.

UI MeSH Term Description Entries
D002415 Cats The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801) Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D004569 Electroencephalography Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain. EEG,Electroencephalogram,Electroencephalograms
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012438 Saccades An abrupt voluntary shift in ocular fixation from one point to another, as occurs in reading. Pursuit, Saccadic,Saccadic Eye Movements,Eye Movement, Saccadic,Eye Movements, Saccadic,Movement, Saccadic Eye,Movements, Saccadic Eye,Pursuits, Saccadic,Saccade,Saccadic Eye Movement,Saccadic Pursuit,Saccadic Pursuits
D012665 Semicircular Canals Three long canals (anterior, posterior, and lateral) of the bony labyrinth. They are set at right angles to each other and are situated posterosuperior to the vestibule of the bony labyrinth (VESTIBULAR LABYRINTH). The semicircular canals have five openings into the vestibule with one shared by the anterior and the posterior canals. Within the canals are the SEMICIRCULAR DUCTS. Semi-Circular Canals,Canal, Semi-Circular,Canal, Semicircular,Semi Circular Canals,Semi-Circular Canal,Semicircular Canal
D013477 Superior Colliculi The anterior pair of the quadrigeminal bodies which coordinate the general behavioral orienting responses to visual stimuli, such as whole-body turning, and reaching. Colliculus, Superior,Optic Lobe, Human,Optic Lobe, Mammalian,Optic Tectum,Anterior Colliculus,Superior Colliculus,Tectum, Optic,Colliculi, Superior,Colliculus, Anterior,Human Optic Lobe,Human Optic Lobes,Mammalian Optic Lobe,Mammalian Optic Lobes,Optic Lobes, Human,Optic Lobes, Mammalian,Optic Tectums,Tectums, Optic
D055724 Electrophysiological Phenomena The electrical properties, characteristics of living organisms, and the processes of organisms or their parts that are involved in generating and responding to electricity. Electrophysiological Concepts,Electrophysiological Processes,Electrophysiologic Concepts,Electrophysiologic Phenomena,Electrophysiological Phenomenon,Electrophysiological Process,Concept, Electrophysiologic,Concept, Electrophysiological,Concepts, Electrophysiologic,Concepts, Electrophysiological,Electrophysiologic Concept,Electrophysiological Concept,Phenomena, Electrophysiologic,Phenomena, Electrophysiological,Phenomenon, Electrophysiological,Process, Electrophysiological,Processes, Electrophysiological

Related Publications

Mayu Takahashi
July 2004, Sheng li ke xue jin zhan [Progress in physiology],
Mayu Takahashi
October 1980, Science (New York, N.Y.),
Mayu Takahashi
January 1972, Bibliotheca ophthalmologica : supplementa ad ophthalmologica,
Mayu Takahashi
December 1991, Archives of ophthalmology (Chicago, Ill. : 1960),
Mayu Takahashi
September 2011, Journal of integrative neuroscience,
Copied contents to your clipboard!