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Setting up a collaborative European human biological monitoring study on occupational exposure to hexavalent chromium. 2019
Tiina Santonen, and
Alessandro Alimonti, and
Beatrice Bocca, and
Radu Corneliu Duca, and
Karen S Galea, and
Lode Godderis, and
Thomas Göen, and
Bruno Gomes, and
Ogier Hanser, and
Ivo Iavicoli, and
Beata Janasik, and
Kate Jones, and
Mirja Kiilunen, and
Holger M Koch, and
Elizabeth Leese, and
Veruscka Leso, and
Henriqueta Louro, and
Sophie Ndaw, and
Simo P Porras, and
Alain Robert, and
Flavia Ruggieri, and
Paul T J Scheepers, and
Maria J Silva, and
Susana Viegas, and
Wojciech Wasowicz, and
Argelia Castano, and
Ovnair Sepai
Finnish Institute of Occupational Health, Finland. Electronic address: tiina.santonen@ttl.fi.
The EU human biomonitoring initiative, HBM4EU, aims to co-ordinate and advance human biomonitoring (HBM) across Europe. Within its remit, the project is gathering new, policy relevant, EU-wide data on occupational exposure to relevant priority chemicals and developing new approaches for occupational biomonitoring. In this manuscript, the hexavalent chromium [Cr(VI)] study design is presented as the first example of this HBM4EU approach. This study involves eight European countries and plans to recruit 400 workers performing Cr(VI) surface treatment e.g. electroplating or stainless steel welding activities. The aim is to collect new data on current occupational exposure to Cr(VI) in Europe and to test new methods for Cr biomonitoring, specifically the analysis of Cr(VI) in exhaled breath condensate (EBC) and Cr in red blood cells (RBC) in addition to traditional urinary total Cr analyses. Furthermore, exposure data will be complemented with early biological effects data, including genetic and epigenetic effects. Personal air samples and wipe samples are collected in parallel to help informing the biomonitoring results. We present standard operational procedures (SOPs) to support the harmonized methodologies for the collection of occupational hygiene and HBM samples in different countries.
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Radu Corneliu Duca, and
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Thomas Göen, and
Bruno Gomes, and
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Ovnair Sepai
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Regulatory toxicology and pharmacology : RTP,
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Radu Corneliu Duca, and
Karen S Galea, and
Lode Godderis, and
Thomas Göen, and
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Kate Jones, and
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Veruscka Leso, and
Henriqueta Louro, and
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Flavia Ruggieri, and
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Argelia Castano, and
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Lode Godderis, and
Thomas Göen, and
Bruno Gomes, and
Ogier Hanser, and
Ivo Iavicoli, and
Beata Janasik, and
Kate Jones, and
Mirja Kiilunen, and
Holger M Koch, and
Elizabeth Leese, and
Veruscka Leso, and
Henriqueta Louro, and
Sophie Ndaw, and
Simo P Porras, and
Alain Robert, and
Flavia Ruggieri, and
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Susana Viegas, and
Wojciech Wasowicz, and
Argelia Castano, and
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Radu Corneliu Duca, and
Karen S Galea, and
Lode Godderis, and
Thomas Göen, and
Bruno Gomes, and
Ogier Hanser, and
Ivo Iavicoli, and
Beata Janasik, and
Kate Jones, and
Mirja Kiilunen, and
Holger M Koch, and
Elizabeth Leese, and
Veruscka Leso, and
Henriqueta Louro, and
Sophie Ndaw, and
Simo P Porras, and
Alain Robert, and
Flavia Ruggieri, and
Paul T J Scheepers, and
Maria J Silva, and
Susana Viegas, and
Wojciech Wasowicz, and
Argelia Castano, and
Ovnair Sepai
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International journal of hygiene and environmental health,
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Alessandro Alimonti, and
Beatrice Bocca, and
Radu Corneliu Duca, and
Karen S Galea, and
Lode Godderis, and
Thomas Göen, and
Bruno Gomes, and
Ogier Hanser, and
Ivo Iavicoli, and
Beata Janasik, and
Kate Jones, and
Mirja Kiilunen, and
Holger M Koch, and
Elizabeth Leese, and
Veruscka Leso, and
Henriqueta Louro, and
Sophie Ndaw, and
Simo P Porras, and
Alain Robert, and
Flavia Ruggieri, and
Paul T J Scheepers, and
Maria J Silva, and
Susana Viegas, and
Wojciech Wasowicz, and
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Ovnair Sepai
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Bollettino della Societa italiana di biologia sperimentale,
