BIOMAT Database Logo BIOMAT Database Logo

Hydrallazine-induced Sjögren's syndrome. 1988

A Darwaza, and P J Lamey, and J M Connell
Department of Oral Medicine and Pathology, Glasgow Dental Hospital and School, Scotland.

4 years after initiation of therapy with hydrallazine hydrochloride (for treatment of hypertension), a 60-year-old male patient developed clinical features of Sjögren's syndrome, with immunological features of drug-induced systemic lupus erythematosus. In addition, the patient described rheumatoid arthritis-like symptoms and had reduced lacrimal and parotid salivary flow, but lacked the typical features of Sjögren's syndrome on labial gland biopsy. 1 year after discontinuation of hydrallazine therapy, the clinical parameters returned to normal.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D006830 Hydralazine A direct-acting vasodilator that is used as an antihypertensive agent. Hydrallazin,Apresoline,Apressin,Apressoline,Hydralazine Hydrochloride,Hydralazine mono-Hydrochloride,Hydrazinophthalazine,Nepresol,Hydralazine mono Hydrochloride,Hydrochloride, Hydralazine,mono-Hydrochloride, Hydralazine
D012793 Sialadenitis INFLAMMATION of salivary tissue (SALIVARY GLANDS), usually due to INFECTION or injuries. Sialitis,Adenitis, Salivary Gland,Chronic Sialadenitis,Irradiation-Induced Sialadenitis,Salivary Gland Inflammation,Sialoadenitis,Adenitides, Salivary Gland,Chronic Sialadenitides,Inflammation, Salivary Gland,Inflammations, Salivary Gland,Irradiation Induced Sialadenitis,Irradiation-Induced Sialadenitides,Salivary Gland Adenitides,Salivary Gland Adenitis,Salivary Gland Inflammations,Sialadenitides,Sialadenitides, Chronic,Sialadenitides, Irradiation-Induced,Sialadenitis, Chronic,Sialadenitis, Irradiation-Induced,Sialitides,Sialoadenitides
D012859 Sjogren's Syndrome Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis. Sicca Syndrome,Sjogren Syndrome,Sjogrens Syndrome,Syndrome, Sicca,Syndrome, Sjogren's

Related Publications

A Darwaza, and P J Lamey, and J M Connell
Anaemia in the hydrallazine-induced Lupus syndrome.
April 1983, Scottish medical journal,
A Darwaza, and P J Lamey, and J M Connell
Hydrallazine-induced hepatitis?
May 1980, British medical journal,
A Darwaza, and P J Lamey, and J M Connell
Hydrallazine-induced cutaneous vasculitis.
January 1980, British medical journal,
A Darwaza, and P J Lamey, and J M Connell
Hydrallazine-induced necrotising vasculitis.
May 1981, British medical journal (Clinical research ed.),
A Darwaza, and P J Lamey, and J M Connell
Hydrallazine-induced SLE-like syndrome presenting as a leg ulcer.
November 1979, British medical journal,
A Darwaza, and P J Lamey, and J M Connell
Epirubicin-induced primary Sjögren's syndrome.
September 1986, Lancet (London, England),
A Darwaza, and P J Lamey, and J M Connell
Specific immunotherapy-induced Sjögren's syndrome.
December 2005, Rheumatology international,
A Darwaza, and P J Lamey, and J M Connell
Phenytoin-induced pseudo-Sjögren's syndrome.
October 1996, British journal of rheumatology,
A Darwaza, and P J Lamey, and J M Connell
HYDRALLAZINE.
February 1977, Lancet (London, England),
A Darwaza, and P J Lamey, and J M Connell
Sjögren's syndrome induced by estrogen therapy.
December 2000, Seminars in arthritis and rheumatism,
Copied contents to your clipboard!