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In an effort to correlate the serum values of potential markers, including CA-125, galactosyltransferase, and total sialic acid, with residual tumor mass after initial surgery, 43 patients with FIGO stage IIb and c, III and IV ovarian cancer were studied. The sensitivity of galactosyltransferase and sialic acid levels was sufficient to correlate their serum values with the corresponding residual tumor mass. Furthermore, 28 patients were histopathologically evaluated for their response to chemotherapy. Determination of these tumor markers did not permit discrimination between small residual disease (less than or equal to 1 cm) and a state of 'no evidence of disease'. Conversely, progression of disease has been associated with a sensitive increase in the level of all three markers. CA-125 has been found to be the most useful of the three for distinguishing between responders and nonresponders.
A Goldhirsch, and
E Berger, and
O Müller, and
R Maibach, and
S Misteli, and
K Buser, and
H Roesler, and
K Brunner
August 1990,
Gynecologic oncology,
A Goldhirsch, and
E Berger, and
O Müller, and
R Maibach, and
S Misteli, and
K Buser, and
H Roesler, and
K Brunner
February 1995,
Annals of medicine,
A Goldhirsch, and
E Berger, and
O Müller, and
R Maibach, and
S Misteli, and
K Buser, and
H Roesler, and
K Brunner
June 1994,
Clinica chimica acta; international journal of clinical chemistry,
A Goldhirsch, and
E Berger, and
O Müller, and
R Maibach, and
S Misteli, and
K Buser, and
H Roesler, and
K Brunner
December 1987,
Geburtshilfe und Frauenheilkunde,
A Goldhirsch, and
E Berger, and
O Müller, and
R Maibach, and
S Misteli, and
K Buser, and
H Roesler, and
K Brunner
August 1986,
Geburtshilfe und Frauenheilkunde,
A Goldhirsch, and
E Berger, and
O Müller, and
R Maibach, and
S Misteli, and
K Buser, and
H Roesler, and
K Brunner
June 1987,
Tumori,
A Goldhirsch, and
E Berger, and
O Müller, and
R Maibach, and
S Misteli, and
K Buser, and
H Roesler, and
K Brunner
May 1985,
Gan no rinsho. Japan journal of cancer clinics,
A Goldhirsch, and
E Berger, and
O Müller, and
R Maibach, and
S Misteli, and
K Buser, and
H Roesler, and
K Brunner
February 1994,
Harefuah,
A Goldhirsch, and
E Berger, and
O Müller, and
R Maibach, and
S Misteli, and
K Buser, and
H Roesler, and
K Brunner
January 1986,
Journal de gynecologie, obstetrique et biologie de la reproduction,
A Goldhirsch, and
E Berger, and
O Müller, and
R Maibach, and
S Misteli, and
K Buser, and
H Roesler, and
K Brunner
September 1989,
Obstetrics and gynecology,
