Biomaterial Database

The Fatty Acid Composition of Vegetable Oils and Their Potential Use in Wound Care. 2019

Anselmo Queiroz Alves, and Valdemiro Amaro da Silva, and Alexandre José Silva Góes, and Mariza Severina Silva, and Gibson Gomes de Oliveira, and Isla Vanessa Gomes Alves Bastos, and Antonio Gomes de Castro Neto, and Antonio José Alves

Anselmo Queiroz Alves, MD, is a Specialist, Maxiclínica Médica Ltda, Recife, Pernambuco, Brazil. Valdemiro Amaro da Silva, Jr, PhD, is Associate Professor, Department of Veterinary Medicine at the Federal Rural University of Pernambuco (UFRPE), Recife, Pernambuco, Brazil. At the Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil, Alexandre José da Silva Góes, PhD, is Associate Professor, Department of Antibiotics; and Mariza Severina Silva is a Master of Sciences student, Postgraduate Program in Pharmaceutical Sciences. Gibson Gomes de Oliveira, PhD, is a postdoctoral student, Research Center on Natural and Synthetic Products, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. At the UFPE, Isla Vanessa Gomes Alves Bastos, PhD, is a postdoctoral student, Department of Antibiotics; Antonio Gomes de Castro Neto, PhD, is Substitute Professor, Department of Physiology and Pharmacology; and Antonio José Alves, PhD, is Titular Professor, Department of Pharmaceutical Sciences. Acknowledgments: The authors thank the Maxiclínica Médica Ltda and CEAN/CETENE for their contributions to research development. The authors have disclosed no financial relationships related to this article. Submitted July 26, 2018; accepted in revised form September 13, 2018; published online ahead of print May 2, 2018.

OBJECTIVE To evaluate the similarities among fatty acid compositions of vegetable oils sold in the Brazilian market and those present in a reference health product used to treat wounds. METHODS The relative amounts of fatty acids in 21 types of vegetable oils, purchased in the Brazilian market, were assessed using gas chromatography-mass spectrometry and flame ionization detection. RESULTS The studied oils had similar fatty acid compositions to the reference product (caprylic acid, 18.8%; capric acid, 17.4%; oleic acid, 27.5%; and linoleic acid, 28.1%). The presence of caprylic acid (10.45% ± 0.07%), capric acid (5.8% ± 0.75%), lauric acid (45.63% ± 0.93%), and myristic acid (16.33% ± 2.23%) were detected in all the vegetable oils tested. Oleic acid (52.94% ± 12.54%) was present in andiroba, avocado, canola, copaiba, olive, palm, pequi, and pracaxi oils and featured prominently in olive oil (75.8%). Linoleic acid (57.09% ± 8.47%) was present in corn, cottonseed, grapeseed, passion fruit, and sunflower oils and in mixed oils (olive with soybean and sunflower with corn and canola). CONCLUSIONS Most of the vegetable oils tested are products of plants from tropical climates, where they are abundant and easy to cultivate. It is possible that a balanced composition of fatty acids obtained from natural sources could be an effective alternative treatment for wounds.

UI	MeSH Term	Description	Entries
D008517	Phytotherapy	Use of plants or herbs to treat diseases or to alleviate pain.	Herb Therapy,Herbal Therapy
D010938	Plant Oils	Oils derived from plants or plant products.	Oils, Plant,Oils, Vegetable,Plant Oil,Vegetable Oil,Vegetable Oils,Oil, Plant,Oil, Vegetable
D001938	Brazil	A country located on the eastern coast of South America, located between Colombia and Peru, that borders the Atlantic Ocean. It is bordered on the north by Venezuela, Guyana, Suriname, and French Guiana, on the south by Uruguay, and on the west by Argentina. The capital is Brasilia.
D005227	Fatty Acids	Organic, monobasic acids derived from hydrocarbons by the equivalent of oxidation of a methyl group to an alcohol, aldehyde, and then acid. Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (Grant & Hackh's Chemical Dictionary, 5th ed)	Aliphatic Acid,Esterified Fatty Acid,Fatty Acid,Fatty Acids, Esterified,Fatty Acids, Saturated,Saturated Fatty Acid,Aliphatic Acids,Acid, Aliphatic,Acid, Esterified Fatty,Acid, Saturated Fatty,Esterified Fatty Acids,Fatty Acid, Esterified,Fatty Acid, Saturated,Saturated Fatty Acids
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000069463	Olive Oil	Oil extracted from fruit of the OLIVE TREE (genus Olea).	Olive Oils,Oil, Olive,Oils, Olive
D000073878	Palm Oil	Nutritive oil extracted from the fleshy mesocarp of the fruit of the African palm tree, Elaeis guineensis.	Palmolein,Oil, Palm
D000074242	Sunflower Oil	Oil derived from the seeds of SUNFLOWER plant, Helianthus.	Sunflower Seed Oil,Oil, Sunflower,Oil, Sunflower Seed,Seed Oil, Sunflower
D000074263	Coconut Oil	Oil derived from fruits of the coconut plant, COCOS NUCIFERA.	Oil, Coconut
D000279	Administration, Cutaneous	The application of suitable drug dosage forms to the skin for either local or systemic effects.	Cutaneous Drug Administration,Dermal Drug Administration,Drug Administration, Dermal,Percutaneous Administration,Skin Drug Administration,Transcutaneous Administration,Transdermal Administration,Administration, Dermal,Administration, Transcutaneous,Administration, Transdermal,Cutaneous Administration,Cutaneous Administration, Drug,Dermal Administration,Drug Administration, Cutaneous,Skin Administration, Drug,Administration, Cutaneous Drug,Administration, Dermal Drug,Administration, Percutaneous,Administrations, Cutaneous,Administrations, Cutaneous Drug,Administrations, Dermal,Administrations, Dermal Drug,Administrations, Percutaneous,Administrations, Transcutaneous,Administrations, Transdermal,Cutaneous Administrations,Cutaneous Administrations, Drug,Cutaneous Drug Administrations,Dermal Administrations,Dermal Drug Administrations,Drug Administrations, Cutaneous,Drug Administrations, Dermal,Drug Skin Administrations,Percutaneous Administrations,Skin Administrations, Drug,Skin Drug Administrations,Transcutaneous Administrations,Transdermal Administrations