Biomaterial Database

Susceptibility of streptomycin-resistant Mycobacterium tuberculosis strains to amikacin. 1988

S E Hoffner, and G Källenius

Department of Bacteriology, National Bacteriological Laboratory, Stockholm, Sweden.

A total of 585 Mycobacterium tuberculosis strains isolated during a three-year period in Sweden were tested for in vitro susceptibility to amikacin in comparison with streptomycin. Resistance to streptomycin was seen in 27 of the isolates (4.6%). These isolates had been obtained from 22 patients, a majority of which were non-European immigrants. All but one of the streptomycin-resistant isolates were susceptible to amikacin. None of 263 streptomycin-susceptible isolates tested was resistant to amikacin. Amikacin appears to be an alternative to streptomycin in the treatment of patients with streptomycin-resistant Mycobacterium tuberculosis.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009169	Mycobacterium tuberculosis	A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation.	Mycobacterium tuberculosis H37Rv
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D004352	Drug Resistance, Microbial	The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS).	Antibiotic Resistance,Antibiotic Resistance, Microbial,Antimicrobial Resistance, Drug,Antimicrobial Drug Resistance,Antimicrobial Drug Resistances,Antimicrobial Resistances, Drug,Drug Antimicrobial Resistance,Drug Antimicrobial Resistances,Drug Resistances, Microbial,Resistance, Antibiotic,Resistance, Drug Antimicrobial,Resistances, Drug Antimicrobial
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly

Related Publications

S E Hoffner, and G Källenius

[Significance of streptomycin resistant strains of Mycobacterium tuberculosis in streptomycin therapy].

January 1951, Problemy tuberkuleza,

S E Hoffner, and G Källenius

[Relationship between streptomycin susceptibility and rpsL mutations of Mycobacterium tuberculosis strains].

September 1997, Kekkaku : [Tuberculosis],

S E Hoffner, and G Källenius

Molecular characterisation of streptomycin-resistant Mycobacterium tuberculosis strains isolated in Poland.

August 2004, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease,

S E Hoffner, and G Källenius

Streptomycin-dependent strains of Mycobacterium tuberculosis.

February 1949, American review of tuberculosis,

S E Hoffner, and G Källenius

[Emergent strains of rifampicin-resistant Mycobacterium tuberculosis complex and susceptibility to isoniazid].

January 2013, Enfermedades infecciosas y microbiologia clinica,

S E Hoffner, and G Källenius

[Streptomycin therapy and development of streptomycin resistant mycobacterium tuberculosis].

January 1950, Rozhledy v tuberkulose,

S E Hoffner, and G Källenius

[Allergy to tuberculin in guinea pigs infected with streptomycin resistant strains of Mycobacterium tuberculosis and treated with streptomycin].

January 1951, Annali dell'Istituto "Carlo Forlanini",