BIOMAT Database Logo BIOMAT Database Logo

Impact of Long-Wavelength Ultraviolet A1 and Visible Light on Light-Skinned Individuals. 2019

Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA.

Solar radiation is known to be a major contributor to the development of skin cancer. Most sunscreen formulations, including those with broad spectrum, offer minimal protection in long-wavelength ultraviolet A1 (UVA1; 370-400 nm) and visible light (VL; 400-700 nm) domain. There is limited information regarding the impact of this broad waveband (VL + UVA1, 370-700 nm) on those with light skin. In this study, ten healthy adult subjects with Fitzpatrick skin phototypes I-III were enrolled. On day 0, subjects' lower back was exposed to a VL + UVA1 dose of 480 J cm-2 . A statistically significant increase in erythema immediately after irradiation compared with subjects' baseline nonirradiated skin was observed. Clinically perceptible erythema with VL + UVA1 is a novel finding since the erythemogenic spectrum of sunlight has primarily been attributed to ultraviolet B and short-wavelength ultraviolet A (320-340 nm). The results emphasize the need for protection against this part of the solar spectra and warrant further investigation.

UI MeSH Term Description Entries
D008027 Light That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range. Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D004307 Dose-Response Relationship, Radiation The relationship between the dose of administered radiation and the response of the organism or tissue to the radiation. Dose Response Relationship, Radiation,Dose-Response Relationships, Radiation,Radiation Dose-Response Relationship,Radiation Dose-Response Relationships,Relationship, Radiation Dose-Response,Relationships, Radiation Dose-Response
D004890 Erythema Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes. Erythemas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012867 Skin The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
D012880 Skin Pigmentation Coloration of the skin. Skin Color,Skin Tone,Color, Skin,Colors, Skin,Pigmentation, Skin,Pigmentations, Skin,Skin Colors,Skin Pigmentations,Skin Tones,Tone, Skin,Tones, Skin

Related Publications

Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Synergistic effects of long-wavelength ultraviolet A1 and visible light on pigmentation and erythema.
May 2018, The British journal of dermatology,
Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Long-wavelength Ultraviolet A1 and Visible Light Photoprotection: A Multimodality Assessment of Dose and Response.
January 2020, Photochemistry and photobiology,
Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Caution regarding testing for long wavelength ultraviolet A1 and visible light effects on human skin in vivo.
January 2020, Photodermatology, photoimmunology & photomedicine,
Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Evaluation of efficacy of antioxidant-enriched sunscreen prodcuts against long wavelength ultraviolet A1 and visible light.
June 2022, International journal of cosmetic science,
Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Evaluation of the protection of sunscreen products against long wavelength ultraviolet A1 and visible light-induced biological effects.
January 2024, Photodermatology, photoimmunology & photomedicine,
Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Lethal effects of long wavelength ultraviolet and visible light on cells. ANL-7535.
December 1968, ANL,
Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Impact of long-wavelength UVA and visible light on melanocompetent skin.
August 2010, The Journal of investigative dermatology,
Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Effects on human skin of repetitive ultraviolet-A1 (UVA1) irradiation and visible light.
April 2001, Photodermatology, photoimmunology & photomedicine,
Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Ultraviolet A1 phototherapy utilizing ultraviolet light-emitting diodes and a short wavelength cutoff filter.
February 2021, Journal of dermatological science,
Indermeet Kohli, and Raheel Zubair, and Alexis B Lyons, and Amanda F Nahhas, and Taylor L Braunberger, and Mohsen Mokhtari, and Eduardo Ruvolo, and Henry W Lim, and Iltefat H Hamzavi
Ultraviolet and short wavelength visible light exposure: why ultraviolet protection alone is not adequate.
January 2006, Journal of long-term effects of medical implants,
Copied contents to your clipboard!