-transparent.png){kind=logo}
The effect of cathepsin D on bovine neurofilament protein was studied biochemically, immunologically, and morphologically. Degradation products of each neurofilament triplet by bovine brain cathepsin D at neutral pH were identified by electrophoresis and immunoblotting with anti-neurofilament antibodies. The 68-kDa subunit was the most susceptive to cathepsin D proteolysis among the triplet proteins. All of the triplet gave rise to partial degradates of the 50-kDa size. The reconstituted fiber from neurofilament triplet proteins and the 68-kDa subunit protein were attacked by cathepsin D and the mode of disruption of the fiber structure was studied by electronmicroscopy.
Related Publications
H Suzuki, and
M Takeda, and
Y Nakamura, and
Y Kato, and
K Tada, and
S Hariguchi, and
T Nishimura
August 1984,
Journal of neurochemistry,
H Suzuki, and
M Takeda, and
Y Nakamura, and
Y Kato, and
K Tada, and
S Hariguchi, and
T Nishimura
October 1984,
Neurochemical research,
H Suzuki, and
M Takeda, and
Y Nakamura, and
Y Kato, and
K Tada, and
S Hariguchi, and
T Nishimura
August 1979,
The Journal of biological chemistry,
H Suzuki, and
M Takeda, and
Y Nakamura, and
Y Kato, and
K Tada, and
S Hariguchi, and
T Nishimura
February 1980,
Journal of neurochemistry,
H Suzuki, and
M Takeda, and
Y Nakamura, and
Y Kato, and
K Tada, and
S Hariguchi, and
T Nishimura
February 1979,
Journal of neurochemistry,
H Suzuki, and
M Takeda, and
Y Nakamura, and
Y Kato, and
K Tada, and
S Hariguchi, and
T Nishimura
February 1996,
The Journal of dairy research,
H Suzuki, and
M Takeda, and
Y Nakamura, and
Y Kato, and
K Tada, and
S Hariguchi, and
T Nishimura
April 1987,
Neurochemical research,
H Suzuki, and
M Takeda, and
Y Nakamura, and
Y Kato, and
K Tada, and
S Hariguchi, and
T Nishimura
February 1992,
The International journal of biochemistry,
H Suzuki, and
M Takeda, and
Y Nakamura, and
Y Kato, and
K Tada, and
S Hariguchi, and
T Nishimura
October 1981,
Biochimica et biophysica acta,
H Suzuki, and
M Takeda, and
Y Nakamura, and
Y Kato, and
K Tada, and
S Hariguchi, and
T Nishimura
December 1975,
Journal of biochemistry,
