-transparent.png){kind=logo}
The clinical case definition for AIDS proposed by WHO for use in Africa was evaluated against HIV antibody status in 72 patients in rural Zaire. Twenty-one (29%) of the patients were antibody-positive. For diagnosing anti-HIV seropositivity, the case definition had a sensitivity of 52%, a specificity of 78%, a positive predictive value of 50% and a negative predictive value of 80%. Calculation of the positive predictive value at different levels of prevalence of HIV infection suggests that the case definition operates at maximum reliability in selected high-risk groups. Modifications to the case definition should be evaluated to try and improve its sensitivity and positive predictive value.
K M De Cock, and
R Colebunders, and
H Francis, and
N Nzilambi, and
M Laga, and
R W Ryder, and
M Bondjobo, and
J B McCormick, and
P Piot
December 1988,
JAMA,
K M De Cock, and
R Colebunders, and
H Francis, and
N Nzilambi, and
M Laga, and
R W Ryder, and
M Bondjobo, and
J B McCormick, and
P Piot
November 1989,
The Journal of infectious diseases,
K M De Cock, and
R Colebunders, and
H Francis, and
N Nzilambi, and
M Laga, and
R W Ryder, and
M Bondjobo, and
J B McCormick, and
P Piot
March 2008,
The Journal of communicable diseases,
K M De Cock, and
R Colebunders, and
H Francis, and
N Nzilambi, and
M Laga, and
R W Ryder, and
M Bondjobo, and
J B McCormick, and
P Piot
January 1988,
Zeitschrift fur arztliche Fortbildung,
K M De Cock, and
R Colebunders, and
H Francis, and
N Nzilambi, and
M Laga, and
R W Ryder, and
M Bondjobo, and
J B McCormick, and
P Piot
January 1994,
Tropical doctor,
K M De Cock, and
R Colebunders, and
H Francis, and
N Nzilambi, and
M Laga, and
R W Ryder, and
M Bondjobo, and
J B McCormick, and
P Piot
August 1992,
AIDS (London, England),
K M De Cock, and
R Colebunders, and
H Francis, and
N Nzilambi, and
M Laga, and
R W Ryder, and
M Bondjobo, and
J B McCormick, and
P Piot
January 1994,
World health forum,
K M De Cock, and
R Colebunders, and
H Francis, and
N Nzilambi, and
M Laga, and
R W Ryder, and
M Bondjobo, and
J B McCormick, and
P Piot
June 1990,
Lancet (London, England),
K M De Cock, and
R Colebunders, and
H Francis, and
N Nzilambi, and
M Laga, and
R W Ryder, and
M Bondjobo, and
J B McCormick, and
P Piot
September 1987,
AIDS (London, England),
K M De Cock, and
R Colebunders, and
H Francis, and
N Nzilambi, and
M Laga, and
R W Ryder, and
M Bondjobo, and
J B McCormick, and
P Piot
January 1988,
Bulletin of the World Health Organization,
