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Application of laser irradiation with porphyrin(s) or their derivatives for the destruction of tumors in humans requires preliminary studies of their localization in normal and malignant tissues. A novel derivative of hematoporphyrin (HP) was prepared. The newly developed hematoporphyrin (DHP) was administered to Fisher rats with bladder tumors and showed greater accumulation in the tumoral tissues. Comparative data on (HP) and (DHP) are presented and discussed in light of the enhanced tumor porphyrin uptake caused by these agents. The homogeneous intense fluorescence noted with DHP-treated animals suggests that total tumor kill curative therapy will be more feasible. The study paves the way to refining increased porphyrin augment phototherapy and laser application in the field of oncology.
M el-Far, and
M Abou-el-Zahab, and
M Ghoneim, and
E Ibrahim
April 1990,
Photochemistry and photobiology,
M el-Far, and
M Abou-el-Zahab, and
M Ghoneim, and
E Ibrahim
July 1983,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
M el-Far, and
M Abou-el-Zahab, and
M Ghoneim, and
E Ibrahim
June 1985,
The Journal of urology,
M el-Far, and
M Abou-el-Zahab, and
M Ghoneim, and
E Ibrahim
November 2008,
Journal of endourology,
M el-Far, and
M Abou-el-Zahab, and
M Ghoneim, and
E Ibrahim
September 1982,
Mayo Clinic proceedings,
M el-Far, and
M Abou-el-Zahab, and
M Ghoneim, and
E Ibrahim
January 1977,
The Annals of otology, rhinology, and laryngology,
M el-Far, and
M Abou-el-Zahab, and
M Ghoneim, and
E Ibrahim
January 1988,
Zeitschrift fur Erkrankungen der Atmungsorgane,
M el-Far, and
M Abou-el-Zahab, and
M Ghoneim, and
E Ibrahim
February 1985,
The Journal of urology,
M el-Far, and
M Abou-el-Zahab, and
M Ghoneim, and
E Ibrahim
November 1986,
Biochemical and biophysical research communications,
M el-Far, and
M Abou-el-Zahab, and
M Ghoneim, and
E Ibrahim
December 1994,
Photochemistry and photobiology,
