Home-Based Computerized Cognitive Training for Postoperative Cognitive Dysfunction After Lung Transplantation in Elderly Population: A Randomized Controlled Trial. 2019

Yanping Song, and Xueling Cui, and Yan Zhang, and Huiying Gao, and Qiaoying Cai, and Zhenzhen Mu
Department of Geriatric Health Care and Management, Heze Medical College.

Postoperative cognitive dysfunction is a severe outcome after lung transplantation, especially in the elderly lung transplant recipients. Home-based computerized cognitive training (CCT) is a widely used intervention for cognition improvement, but its efficacy has not been validated in this population. A randomized controlled trial was conducted to analyze the effect of CCT on elderly lung transplant recipients. The participants received either an 8-week CCT intervention or usual care. The changes of cognitive function were assessed between preintervention (T1), postintervention (T2), and 12 weeks postintervention (T3). Among the 46 participants, 91.3% completed the interventions. The CCT group performed better than the control group on Digit-Span Forward Test (T3: p = 0.0044) and Verbal Fluency Test (T3: p = 0.0331), indicating the efficacy of CCT on verbal memory in the elderly lung transplant recipients. Although varied impacts were observed on different cognitive domains, it seems promising to use CCT on the elderly population after lung transplantation.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000072466 Cognitive Remediation Behavioral treatment that uses drill and practice, compensatory and adaptive strategies to facilitate improvement in targeted learning areas. Remediation, Cognitive
D000079690 Postoperative Cognitive Complications COGNITIVE IMPAIRMENT or functional decline after a surgical procedure. Postoperative Cognitive Decline,Postoperative Cognitive Disorders,Postoperative Cognitive Dysfunction,Postoperative Dementia,Cognitive Complication, Postoperative,Cognitive Decline, Postoperative,Cognitive Disorder, Postoperative,Cognitive Dysfunction, Postoperative,Complication, Postoperative Cognitive,Decline, Postoperative Cognitive,Dementia, Postoperative,Dementias, Postoperative,Disorder, Postoperative Cognitive,Dysfunction, Postoperative Cognitive,Postoperative Cognitive Complication,Postoperative Cognitive Disorder,Postoperative Dementias
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D013813 Therapy, Computer-Assisted Computer systems utilized as adjuncts in the treatment of disease. Computer-Assisted Therapy,Protocol-Directed Therapy, Computer-Assisted,Computer-Assisted Protocol-Directed Therapy,Therapy, Computer-Assisted Protocol-Directed,Computer Assisted Protocol Directed Therapy,Computer Assisted Therapy,Computer-Assisted Protocol-Directed Therapies,Computer-Assisted Therapies,Protocol Directed Therapy, Computer Assisted,Protocol-Directed Therapies, Computer-Assisted,Therapies, Computer-Assisted,Therapies, Computer-Assisted Protocol-Directed,Therapy, Computer Assisted,Therapy, Computer Assisted Protocol Directed
D016040 Lung Transplantation The transference of either one or both of the lungs from one human or animal to another. Grafting, Lung,Transplantation, Lung,Graftings, Lung,Lung Grafting,Lung Graftings,Lung Transplantations,Transplantations, Lung
D017063 Outcome Assessment, Health Care Research aimed at assessing the quality and effectiveness of health care as measured by the attainment of a specified end result or outcome. Measures include parameters such as improved health, lowered morbidity or mortality, and improvement of abnormal states (such as elevated blood pressure). Assessment, Outcome,Outcome Assessment,Outcome Assessment (Health Care),Outcomes Research,Assessment, Outcomes,Outcome Measures,Outcome Studies,Outcomes Assessment,Assessment, Outcome (Health Care),Assessments, Outcome,Assessments, Outcome (Health Care),Assessments, Outcomes,Measure, Outcome,Measures, Outcome,Outcome Assessments,Outcome Assessments (Health Care),Outcome Measure,Outcome Study,Outcomes Assessments,Research, Outcomes,Studies, Outcome,Study, Outcome

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