Magnetic resonance fingerprinting of temporal lobe white matter in mesial temporal lobe epilepsy. 2019

Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
Department of Neurology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Mesial temporal lobe epilepsy (MTLE) is a network disorder. We aimed to quantify the white matter alterations in the temporal lobe of MTLE patients with hippocampal sclerosis (MTLE-HS) by using magnetic resonance fingerprinting (MRF), a novel imaging technique, which allows simultaneous measurements of multiple parameters with a single acquisition. We consecutively recruited 27 unilateral MTLE-HS patients and 22 healthy controls. Measurements including T1, T2, and PD values in the temporopolar white matter and temporal stem were recorded and analyzed. We found increased T2 value in both sides, and increased T1 value in the ipsilateral temporopolar white matter of MTLE-HS patients, as compared with healthy controls. The T1 and T2 values were higher in the ipsilateral than the contralateral side. In the temporal stem, increased T1 and T2 values in the ipsilateral side of the MTLE-HS patients were also observed. Only increased T2 values were observed in the contralateral temporal stem. No significant differences in PD values were observed in either the temporopolar white matter or temporal stem of the MTLE-HS patients. Correlation analysis revealed that T1 and T2 values in the ipsilateral temporopolar white matter were negatively correlated with the age at epilepsy onset. By using MRF, we were able to assess the alterations of T1 and T2 in the temporal lobe white matter of MTLE-HS patients. MRF could be a promising imaging technique in identifying mild changes in MTLE patients, which might optimize the pre-surgical evaluation and therapeutic interventions in these patients.

UI MeSH Term Description Entries
D007091 Image Processing, Computer-Assisted A technique of inputting two-dimensional or three-dimensional images into a computer and then enhancing or analyzing the imagery into a form that is more useful to the human observer. Biomedical Image Processing,Computer-Assisted Image Processing,Digital Image Processing,Image Analysis, Computer-Assisted,Image Reconstruction,Medical Image Processing,Analysis, Computer-Assisted Image,Computer-Assisted Image Analysis,Computer Assisted Image Analysis,Computer Assisted Image Processing,Computer-Assisted Image Analyses,Image Analyses, Computer-Assisted,Image Analysis, Computer Assisted,Image Processing, Biomedical,Image Processing, Computer Assisted,Image Processing, Digital,Image Processing, Medical,Image Processings, Medical,Image Reconstructions,Medical Image Processings,Processing, Biomedical Image,Processing, Digital Image,Processing, Medical Image,Processings, Digital Image,Processings, Medical Image,Reconstruction, Image,Reconstructions, Image
D008279 Magnetic Resonance Imaging Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques. Chemical Shift Imaging,MR Tomography,MRI Scans,MRI, Functional,Magnetic Resonance Image,Magnetic Resonance Imaging, Functional,Magnetization Transfer Contrast Imaging,NMR Imaging,NMR Tomography,Tomography, NMR,Tomography, Proton Spin,fMRI,Functional Magnetic Resonance Imaging,Imaging, Chemical Shift,Proton Spin Tomography,Spin Echo Imaging,Steady-State Free Precession MRI,Tomography, MR,Zeugmatography,Chemical Shift Imagings,Echo Imaging, Spin,Echo Imagings, Spin,Functional MRI,Functional MRIs,Image, Magnetic Resonance,Imaging, Magnetic Resonance,Imaging, NMR,Imaging, Spin Echo,Imagings, Chemical Shift,Imagings, Spin Echo,MRI Scan,MRIs, Functional,Magnetic Resonance Images,Resonance Image, Magnetic,Scan, MRI,Scans, MRI,Shift Imaging, Chemical,Shift Imagings, Chemical,Spin Echo Imagings,Steady State Free Precession MRI
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D004833 Epilepsy, Temporal Lobe A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321). Epilepsy, Benign Psychomotor, Childhood,Benign Psychomotor Epilepsy, Childhood,Childhood Benign Psychomotor Epilepsy,Epilepsy, Lateral Temporal,Epilepsy, Uncinate,Epilepsies, Lateral Temporal,Epilepsies, Temporal Lobe,Epilepsies, Uncinate,Lateral Temporal Epilepsies,Lateral Temporal Epilepsy,Temporal Lobe Epilepsies,Temporal Lobe Epilepsy,Uncinate Epilepsies,Uncinate Epilepsy
D005260 Female Females
D006624 Hippocampus A curved elevation of GRAY MATTER extending the entire length of the floor of the TEMPORAL HORN of the LATERAL VENTRICLE (see also TEMPORAL LOBE). The hippocampus proper, subiculum, and DENTATE GYRUS constitute the hippocampal formation. Sometimes authors include the ENTORHINAL CORTEX in the hippocampal formation. Ammon Horn,Cornu Ammonis,Hippocampal Formation,Subiculum,Ammon's Horn,Hippocampus Proper,Ammons Horn,Formation, Hippocampal,Formations, Hippocampal,Hippocampal Formations,Hippocampus Propers,Horn, Ammon,Horn, Ammon's,Proper, Hippocampus,Propers, Hippocampus,Subiculums
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

Related Publications

Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
August 2018, Medicine,
Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
May 2014, Epilepsia,
Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
January 2021, Neurosurgery,
Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
February 2016, Epilepsy research,
Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
July 2021, Neurosurgery,
Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
March 2009, Journal of neurology, neurosurgery, and psychiatry,
Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
December 2020, Acta neurologica Belgica,
Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
July 2014, Neuroreport,
Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
September 2013, Journal of neurology,
Kang Wang, and Xiaozhi Cao, and Dengchang Wu, and Congyu Liao, and Jianfang Zhang, and Caihong Ji, and Jianhui Zhong, and Hongjian He, and Yanxing Chen
January 2012, NeuroImage. Clinical,
Copied contents to your clipboard!