The Mallory-Weiss lesion as a cause of upper gastrointestinal bleeding. 1979

A I Stern, and M G Korman, and P S Hunt, and J Hansky, and H S Hillman, and G T Schmidt

A prospective study of patients with upper gastrointestinal bleeding admitted to a haematemesis and melaena unit has revealed an incidence of Mallory-Weiss tears of 8% (59 of 762 patients undergoing endoscopy). Prior vomiting was present in 60% and an associated upper gastrointestinal lesion in 44 percent. The majority of patients had a recent ingestion of alcohol and/or analgesics, whilst 34% had chronic heavy alcohol intake. Approximately 50% of patients required no blood transfusion, while 37% had over three units of blood. No patient in the group required surgical intervention, and one patient died because of general debility. This study suggests that the Mallory-Weiss tear accounts for a significant proportion of patients admitted with upper gastrointestinal bleeding, but that the mortality and morbidity are low.

UI MeSH Term Description Entries
D008297 Male Males
D008309 Mallory-Weiss Syndrome A condition characterized by mucosal tears at the ESOPHAGOGASTRIC JUNCTION, sometimes with HEMATEMESIS. Typically it is caused by forceful bouts of retching or VOMITING. Gastroesophageal Laceration-Hemorrhage,Mallory-Weiss Laceration,Mallory-Weiss Tear,Mucosal Lacerations-Gastroesophageal Junction,Gastroesophageal Laceration Hemorrhage,Gastroesophageal Laceration-Hemorrhages,Junction, Mucosal Lacerations-Gastroesophageal,Junctions, Mucosal Lacerations-Gastroesophageal,Laceration, Mallory-Weiss,Laceration-Hemorrhage, Gastroesophageal,Laceration-Hemorrhages, Gastroesophageal,Lacerations-Gastroesophageal Junction, Mucosal,Lacerations-Gastroesophageal Junctions, Mucosal,Mallory Weiss Laceration,Mallory Weiss Syndrome,Mallory Weiss Tear,Mucosal Lacerations Gastroesophageal Junction,Mucosal Lacerations-Gastroesophageal Junctions,Syndrome, Mallory-Weiss
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D005260 Female Females
D006471 Gastrointestinal Hemorrhage Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM. Hematochezia,Hemorrhage, Gastrointestinal,Gastrointestinal Hemorrhages,Hematochezias
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

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