Biomaterial Database

Toxicity of inhaled isobutyl nitrite in BALB/c mice: systemic and immunotoxic studies. 1988

D M Lewis, and D W Lynch

Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, Morgantown, WV 26505.

UI	MeSH Term	Description	Entries
D007111	Immunity, Cellular	Manifestations of the immune response which are mediated by antigen-sensitized T-lymphocytes via lymphokines or direct cytotoxicity. This takes place in the absence of circulating antibody or where antibody plays a subordinate role.	Cell-Mediated Immunity,Cellular Immune Response,Cell Mediated Immunity,Cell-Mediated Immunities,Cellular Immune Responses,Cellular Immunities,Cellular Immunity,Immune Response, Cellular,Immune Responses, Cellular,Immunities, Cell-Mediated,Immunities, Cellular,Immunity, Cell-Mediated,Response, Cellular Immune
D008297	Male		Males
D008708	Methemoglobinemia	The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)	Methemoglobinemias
D008807	Mice, Inbred BALB C	An inbred strain of mouse that is widely used in IMMUNOLOGY studies and cancer research.	BALB C Mice, Inbred,BALB C Mouse, Inbred,Inbred BALB C Mice,Inbred BALB C Mouse,Mice, BALB C,Mouse, BALB C,Mouse, Inbred BALB C,BALB C Mice,BALB C Mouse
D009573	Nitrites	Salts of nitrous acid or compounds containing the group NO2-. The inorganic nitrites of the type MNO2 (where M	Nitrite
D009929	Organ Size	The measurement of an organ in volume, mass, or heaviness.	Organ Volume,Organ Weight,Size, Organ,Weight, Organ
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D005260	Female		Females
D000280	Administration, Inhalation	The administration of drugs by the respiratory route. It includes insufflation into the respiratory tract.	Drug Administration, Inhalation,Drug Administration, Respiratory,Drug Aerosol Therapy,Inhalation Drug Administration,Inhalation of Drugs,Respiratory Drug Administration,Aerosol Drug Therapy,Aerosol Therapy, Drug,Drug Therapy, Aerosol,Inhalation Administration,Administration, Inhalation Drug,Administration, Respiratory Drug,Therapy, Aerosol Drug,Therapy, Drug Aerosol
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia

Related Publications

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Prechronic inhalation toxicity studies of isobutyl nitrite.

August 1992, Fundamental and applied toxicology : official journal of the Society of Toxicology,

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An evaluation of the immunotoxic potential of isobutyl nitrite.

September 1983, MMWR. Morbidity and mortality weekly report,

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Increased tumor growth in mice exposed to inhaled isobutyl nitrite.

January 1999, Toxicology letters,

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Immunotoxic effects of perfluorononanoic acid on BALB/c mice.

October 2008, Toxicological sciences : an official journal of the Society of Toxicology,

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[Immunotoxic effect of herbicide simazine exposure in BALB/c mice].

October 2009, Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases,

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Isobutyl nitrite toxicity by ingestion.

May 1980, Annals of internal medicine,

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Inhaled isobutyl nitrite impairs T cell reactivity.

January 1991, Advances in experimental medicine and biology,

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Immunotoxic effects of imidacloprid following 28 days of oral exposure in BALB/c mice.

May 2013, Environmental toxicology and pharmacology,

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[Studies on the carcinogenesis of sodium nitrite and/or ethambutol in BALB/c/Cb/Sc mice].

January 1975, Lavori dell'Istituto di anatomia e istologia patologica, Universita degli studi di Perugia,