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A Gene Expression Atlas of the Domestic Water Buffalo (Bubalus bubalis). 2019

Rachel Young, and Lucas Lefevre, and Stephen J Bush, and Akshay Joshi, and Salam Herojeet Singh, and Santosh Kumar Jadhav, and Velu Dhanikachalam, and Zofia M Lisowski, and Daniela Iamartino, and Kim M Summers, and John L Williams, and Alan L Archibald, and Suresh Gokhale, and Satish Kumar, and David A Hume
The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

The domestic water buffalo (Bubalus bubalis) makes a major contribution to the global agricultural economy in the form of milk, meat, hides, and draught power. The global water buffalo population is predominantly found in Asia, and per head of population more people depend upon the buffalo than on any other livestock species. Despite its agricultural importance, there are comparatively fewer genomic and transcriptomic resources available for buffalo than for other livestock species. We have generated a large-scale gene expression atlas covering multiple tissue and cell types from all major organ systems collected from three breeds of riverine water buffalo (Mediterranean, Pandharpuri and Bhadawari) and used the network analysis tool Graphia Professional to identify clusters of genes with similar expression profiles. Alongside similar data, we and others have generated for ruminants as part of the Functional Annotation of Animal Genomes Consortium; this comprehensive transcriptome supports functional annotation and comparative analysis of the water buffalo genome.

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