BIOMAT Database Logo BIOMAT Database Logo

Synthesis and Prior Misidentification of 4-tert-Butyl-2,6-dinitrobenzaldehyde. 2019

Daniel J Martin, and Brandon Q Mercado, and James M Mayer
Department of Chemistry , Yale University , New Haven , Connecticut 06520-8107 , United States.

Substituted 2,6-dinitrobenzaldehydes are valuable synthetic precursors and have been prepared by several methods. We report here that one reported synthetic method actually forms the 3,5-dinitro isomer, 4-tert-butyl-3,5-dinitrobenzaldehyde, instead of the claimed 2,6-isomer, 4-tert-butyl-2,6-dinitrobenzaldehyde. Improved syntheses for the large-scale preparation of both compounds and their single-crystal X-ray structures are described.

UI MeSH Term Description Entries

Related Publications

Daniel J Martin, and Brandon Q Mercado, and James M Mayer
Photochemistry of N-sec-butyl-4-tert-butyl-2,6-dinitroaniline.
January 1974, Journal of agricultural and food chemistry,
Daniel J Martin, and Brandon Q Mercado, and James M Mayer
Toxicity of 2,6-Di-tert-butyl-4-Nitrophenol (DBNP).
April 2001, Applied occupational and environmental hygiene,
Daniel J Martin, and Brandon Q Mercado, and James M Mayer
Soil persistence and metabolism of N-sec-butyl-4-tert-butyl-2,6-dinitroaniline.
January 1974, Journal of agricultural and food chemistry,
Daniel J Martin, and Brandon Q Mercado, and James M Mayer
2,6-Di-tert-butyl-4-(morpholinometh-yl)-phenol monohydrate.
January 2008, Acta crystallographica. Section E, Structure reports online,
Daniel J Martin, and Brandon Q Mercado, and James M Mayer
2,6-Di-tert-butyl-4-(methoxy-meth-yl)phenol.
February 2008, Acta crystallographica. Section E, Structure reports online,
Daniel J Martin, and Brandon Q Mercado, and James M Mayer
Antiinflammatory 2,6-di-tert-butyl-4-(2-arylethenyl)phenols.
January 1989, Journal of medicinal chemistry,
Daniel J Martin, and Brandon Q Mercado, and James M Mayer
Short synthesis of tert-butyl-hydroxylated 3,5-di-tert-butyl-4-hydroxybenzaldehyde: Synthesis of tert-butyl-hydroxylated S-2474.
February 2003, The Journal of organic chemistry,
Daniel J Martin, and Brandon Q Mercado, and James M Mayer
2,6-Di-tert-butyl-4-(dimethyl-amino-meth-yl)phenol.
December 2007, Acta crystallographica. Section E, Structure reports online,
Daniel J Martin, and Brandon Q Mercado, and James M Mayer
4-tert-Butyl-N-[(2,6-dimethyl-phen-yl)carbamothio-yl]benzamide.
September 2012, Acta crystallographica. Section E, Structure reports online,
Daniel J Martin, and Brandon Q Mercado, and James M Mayer
2,6-Di-tert-butyl-4-[(N-methyl-anilino)meth-yl]phenol.
January 2008, Acta crystallographica. Section E, Structure reports online,
Copied contents to your clipboard!