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The in vitro activity of temafloxacin, a new difluoro quinolone agent, against 725 bacterial isolates representing 32 species was evaluated in comparison with that of ciprofloxacin. Temafloxacin inhibited the majority of Enterobacteriaceae isolates at a concentration of less than or equal to 0.5 microgram/ml. It was also extremely active against Acinetobacter spp. and Aeromonas hydrophila. Its activity was 2-8 fold less than that of ciprofloxacin against most gram-negative isolates. Methicillin-susceptible and methicillin-resistant Staphylococcus aureus, coagulase-negative Staphylococcus spp., Streptococcus spp., Listeria monocytogenes, Bacillus spp. and group JK corynebacteria were inhibited at concentrations equal to that of ciprofloxacin.
K V Rolston, and
D H Ho, and
B LeBlanc, and
G Gooch, and
G P Bodey
February 1988,
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology,
K V Rolston, and
D H Ho, and
B LeBlanc, and
G Gooch, and
G P Bodey
January 1990,
Chemotherapy,
K V Rolston, and
D H Ho, and
B LeBlanc, and
G Gooch, and
G P Bodey
January 1989,
Diagnostic microbiology and infectious disease,
K V Rolston, and
D H Ho, and
B LeBlanc, and
G Gooch, and
G P Bodey
January 1985,
Scandinavian journal of infectious diseases,
K V Rolston, and
D H Ho, and
B LeBlanc, and
G Gooch, and
G P Bodey
January 1989,
Antimicrobial agents and chemotherapy,
K V Rolston, and
D H Ho, and
B LeBlanc, and
G Gooch, and
G P Bodey
January 1991,
Chemotherapy,
K V Rolston, and
D H Ho, and
B LeBlanc, and
G Gooch, and
G P Bodey
February 1992,
Antimicrobial agents and chemotherapy,
K V Rolston, and
D H Ho, and
B LeBlanc, and
G Gooch, and
G P Bodey
July 2002,
Chemotherapy,
K V Rolston, and
D H Ho, and
B LeBlanc, and
G Gooch, and
G P Bodey
November 1987,
Antimicrobial agents and chemotherapy,
K V Rolston, and
D H Ho, and
B LeBlanc, and
G Gooch, and
G P Bodey
December 1991,
The Journal of antimicrobial chemotherapy,
