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In a chronic feeding study adult male Fischer-344 rats (n = 12) were fed a nutritionally complete liquid diet containing 10% (w/v) ethanol for 40 days while control animals (n = 12) were pair fed a nutritionally complete isocaloric diet in which dextrose was substituted for ethanol. Treated animals were gradually introduced to and withdrawn from the 10% diet. At the end of the study and at sacrifice ethanol-fed rats had gained slightly more weight than pair-fed controls. They also showed a significant decrease in total thyroxine, free thyroxine, L-triiodothyronine, reverse L-triiodothyronine, and basal thyroid-stimulating hormone. These differences did not appear to result from caloric deprivation alone. Possible explanations for some of these thyroidal changes are discussed.
G A Mason, and
D A Stanley, and
C H Walker, and
H Hashimoto, and
L R Noonan, and
A J Prange
December 1992,
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G A Mason, and
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A J Prange
March 1994,
Endocrinology,
G A Mason, and
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March 1990,
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G A Mason, and
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G A Mason, and
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January 2001,
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G A Mason, and
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September 1992,
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G A Mason, and
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G A Mason, and
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G A Mason, and
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Alcoholism, clinical and experimental research,
G A Mason, and
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L R Noonan, and
A J Prange
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Alcoholism, clinical and experimental research,
