Gone Wildling: Building a Better Lab Mouse. 2019


By implanting wild female mice with common lab mouse embryos, researchers created a "wildling" model that combines natural microbiota with tractable genetics and, as a result, may improve the value of translational research.

UI MeSH Term Description Entries
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus
D057170 Translational Research, Biomedical The endeavour to traverse a specific step of the translation process of turning an observation in the laboratory, clinic, or community into an intervention that will improve the health of individuals and the public. (from Nat Rev Drug Discov. 2018 July ; 17(7): 455–456.) Translational Medical Research,Translational Research,Translational Research, Medical,Biomedical Translational Research,Medical Research, Translational,Medical Translational Research,Research, Biomedical Translational,Research, Medical Translational,Research, Translational,Research, Translational Medical
D064307 Microbiota The full collection of microbes (bacteria, fungi, virus, etc.) that naturally exist within a particular biological niche such as an organism, soil, a body of water, etc. Human Microbiome,Microbiome,Microbiome, Human,Microbial Community,Microbial Community Composition,Microbial Community Structure,Community Composition, Microbial,Community Structure, Microbial,Community, Microbial,Composition, Microbial Community,Human Microbiomes,Microbial Communities,Microbial Community Compositions,Microbial Community Structures,Microbiomes,Microbiotas

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