Unexplained Case of Intrauterine Fetal Demise Resolved: Case Report and Literature Review. 2019

Kimberly L Klein, and Amanda Tchakarov
Department of Pathology and Laboratory Medicine, University of Houston Health Science Center, Houston, TX, USA.

The association between umbilical cord ulceration and intestinal atresia has been previously established. Umbilical cord ulceration is a seemingly rare, potentially life threatening complication of intestinal atresia. The exact etiological mechanism is unknown and recent literature indicates more intensive prenatal monitoring may alter fetal outcome. In this paper we will review the previously reported cases of intestinal atresia complicated by umbilical cord ulceration and comment on the pathophysiological mechanism of umbilical cord ulceration, with emphasis on the unique location of the atresia at the gastroduodenal junction in our case.

UI MeSH Term Description Entries
D007409 Intestinal Atresia Congenital obliteration of the lumen of the intestine, with the ILEUM involved in 50% of the cases and the JEJUNUM and DUODENUM following in frequency. It is the most frequent cause of INTESTINAL OBSTRUCTION in NEWBORNS. (From Stedman, 25th ed) Atresia, Intestinal,Apple Peel Small Bowel Syndrome,Apple Peel Syndrome,Apple-Peel Intestinal Atresia,Congenital Intestinal Atresia,Familial Apple Peel Jejunal Atresia,Jejunal Atresia,Apple Peel Intestinal Atresia,Apple Peel Syndromes,Apple-Peel Intestinal Atresias,Atresia, Apple-Peel Intestinal,Atresia, Congenital Intestinal,Atresia, Jejunal,Atresias, Apple-Peel Intestinal,Atresias, Congenital Intestinal,Congenital Intestinal Atresias,Intestinal Atresia, Apple-Peel,Intestinal Atresia, Congenital,Intestinal Atresias, Apple-Peel,Intestinal Atresias, Congenital
D010920 Placenta A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES). Placentoma, Normal,Placentome,Placentas,Placentomes
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D014456 Ulcer A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue. Ulcers
D014470 Umbilical Cord The flexible rope-like structure that connects a developing FETUS to the PLACENTA in mammals. The cord contains blood vessels which carry oxygen and nutrients from the mother to the fetus and waste products away from the fetus. Cord, Umbilical,Cords, Umbilical,Umbilical Cords
D020964 Embryo Loss Early pregnancy loss during the EMBRYO, MAMMALIAN stage of development. In the human, this period comprises the second through eighth week after fertilization. Blastocyst Disintegration,Embryo Death,Embryo Disintegration,Embryo Resorption,Disintegration of Blastocyst,Disintegration of Embryo,Death, Embryo,Disintegration, Blastocyst,Embryo Deaths,Resorption, Embryo

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