Ophthalmological lesions after long-term dialysis treatment. 1988

J Svĕrák, and D Hejcmanová, and J Peregrin, and J Erben
School of Medicine, Charles University, Hradec Králové.

In the sphere of dialysis treatment, the questions of adequacy of this form of treatment are receiving increasing attention. One of the criteria for the evaluation of this problem is no doubt the functional and anatomical state of the body. As the eye findings form an integral part of the entire clinical picture, the occurrence of pathological ophthalmologic lesions found after long term dialysis treatment (LTDT) can be used as a criterion of adequacy of the chosen treatment. Eye findings were evaluated in 12 patients with chronic renal insufficiency treated by haemodialysis for at least 10 years. On the external eye segment, most evident were degenerative changes of the pinguecula type, occurring in all patients. In all cases we also observed a massive disturbance of the retinal electrical activity (REA). In 58% of all examined patients we found a peculiar yellow-brownish pigmentation of the eye background. Greater or smaller alterations in the intra-ocular microcirculation in the chorioideal, retinal and papillary circulation regions were proven fluoroangiographically in all patients. In 5 eyes a marked disturbance of central vision was found as a result of pathological changes of the retinal centres or atrophy of the optic nerve. We may sum up that the haemodialysis treatment is yet not able to maintain all functions of the body at a satisfactory level.

UI MeSH Term Description Entries
D008297 Male Males
D009887 Ophthalmoscopy Examination of the interior of the eye with an ophthalmoscope. Ophthalmoscopies
D004596 Electroretinography Recording of electric potentials in the retina after stimulation by light. Electroretinographies
D005074 Evoked Potentials, Visual The electric response evoked in the cerebral cortex by visual stimulation or stimulation of the visual pathways. Visual Evoked Response,Evoked Potential, Visual,Evoked Response, Visual,Evoked Responses, Visual,Potential, Visual Evoked,Potentials, Visual Evoked,Response, Visual Evoked,Responses, Visual Evoked,Visual Evoked Potential,Visual Evoked Potentials,Visual Evoked Responses
D005128 Eye Diseases Diseases affecting the eye. Eye Disorders,Eye Disease,Eye Disorder
D005260 Female Females
D005451 Fluorescein Angiography Visualization of a vascular system after intravenous injection of a fluorescein solution. The images may be photographed or televised. It is used especially in studying the retinal and uveal vasculature. Fluorescence Angiography,Fundus Fluorescence Photography,Angiography, Fluorescein,Angiography, Fluorescence,Fluorescence Photography, Fundus,Photography, Fundus Fluorescence
D006435 Renal Dialysis Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION. Dialysis, Extracorporeal,Dialysis, Renal,Extracorporeal Dialysis,Hemodialysis,Dialyses, Extracorporeal,Dialyses, Renal,Extracorporeal Dialyses,Hemodialyses,Renal Dialyses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000091402 Prohibitins Ubiquitously expressed conserved proteins associated with multiple functions including APOPTOSIS; CELL PROLIFERATION, regulations of various immune and mitochondrial functions, and cellular stress responses. Prohibitin 1 and prohibitin 2 form a ring-shaped complex in the INNER MITOCHONDRIAL MEMBRANE. Prohibitin

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