| D009569 |
Nitric Oxide |
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP. |
Endogenous Nitrate Vasodilator,Mononitrogen Monoxide,Nitric Oxide, Endothelium-Derived,Nitrogen Monoxide,Endothelium-Derived Nitric Oxide,Monoxide, Mononitrogen,Monoxide, Nitrogen,Nitrate Vasodilator, Endogenous,Nitric Oxide, Endothelium Derived,Oxide, Nitric,Vasodilator, Endogenous Nitrate |
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| D001921 |
Brain |
The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. |
Encephalon |
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| D002460 |
Cell Line |
Established cell cultures that have the potential to propagate indefinitely. |
Cell Lines,Line, Cell,Lines, Cell |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D000069336 |
Neurovascular Coupling |
Mechanism by which changes in neural activity are tightly associated with regional cortical HEMODYNAMICS and metabolism changes. The association is often inferred from NEUROIMAGING signals (e.g., fMRI; or NIR SPECTROSCOPY). |
Cortical Hemodynamic Response,Cortical Hemodynamic Responses,Hemodynamic Brain Response,Hemodynamic Brain Responses,Brain Response, Hemodynamic,Brain Responses, Hemodynamic,Coupling, Neurovascular,Couplings, Neurovascular,Hemodynamic Response, Cortical,Hemodynamic Responses, Cortical,Neurovascular Couplings,Response, Cortical Hemodynamic,Response, Hemodynamic Brain,Responses, Cortical Hemodynamic,Responses, Hemodynamic Brain |
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| D042783 |
Endothelial Cells |
Highly specialized EPITHELIAL CELLS that line the HEART; BLOOD VESSELS; and lymph vessels, forming the ENDOTHELIUM. They are polygonal in shape and joined together by TIGHT JUNCTIONS. The tight junctions allow for variable permeability to specific macromolecules that are transported across the endothelial layer. |
Capillary Endothelial Cells,Lymphatic Endothelial Cells,Vascular Endothelial Cells,Capillary Endothelial Cell,Cell, Capillary Endothelial,Cell, Endothelial,Cell, Lymphatic Endothelial,Cell, Vascular Endothelial,Cells, Capillary Endothelial,Cells, Endothelial,Cells, Lymphatic Endothelial,Cells, Vascular Endothelial,Endothelial Cell,Endothelial Cell, Capillary,Endothelial Cell, Lymphatic,Endothelial Cell, Vascular,Endothelial Cells, Capillary,Endothelial Cells, Lymphatic,Endothelial Cells, Vascular,Lymphatic Endothelial Cell,Vascular Endothelial Cell |
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| D055806 |
Microvessels |
The finer blood vessels of the vasculature that are generally less than 100 microns in internal diameter. |
Microvasculature,Microvascular Network,Microvascular Networks,Microvessel,Network, Microvascular,Networks, Microvascular |
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| D018094 |
Receptors, Metabotropic Glutamate |
Cell surface proteins that bind glutamate and act through G-proteins to influence second messenger systems. Several types of metabotropic glutamate receptors have been cloned. They differ in pharmacology, distribution, and mechanisms of action. |
Glutamate Receptors, Metabotropic,Metabotropic Glutamate Receptors,Receptors, Glutamate, Metabotropic,Metabotropic Glutamate Receptor,Glutamate Receptor, Metabotropic,Receptor, Metabotropic Glutamate |
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| D018698 |
Glutamic Acid |
A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM. |
Aluminum L-Glutamate,Glutamate,Potassium Glutamate,D-Glutamate,Glutamic Acid, (D)-Isomer,L-Glutamate,L-Glutamic Acid,Aluminum L Glutamate,D Glutamate,Glutamate, Potassium,L Glutamate,L Glutamic Acid,L-Glutamate, Aluminum |
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| D020013 |
Calcium Signaling |
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins. |
Calcium Oscillations,Calcium Waves,Calcium Puffs,Calcium Sparks,Calcium Spikes,Calcium Oscillation,Calcium Puff,Calcium Signalings,Calcium Spark,Calcium Spike,Calcium Wave,Oscillation, Calcium,Oscillations, Calcium,Puff, Calcium,Puffs, Calcium,Signaling, Calcium,Signalings, Calcium,Spark, Calcium,Sparks, Calcium,Spike, Calcium,Spikes, Calcium,Wave, Calcium,Waves, Calcium |
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