BIOMAT Database Logo BIOMAT Database Logo

"Ia-like" antigens on human T cells. 1979

M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward

Human T lymphocytes have been tested for cell surface p. 28,33 "Ia-like" heteroantigen and DRw alloantigens. Small numbers (1--5%) of sheep (E) rosette or T antigen-positive, surface immunoglobulin-negative (E+, T+, smIg-) T cells were Ia+; these cells appeared to be restricted to the TG subset. Following activation by allogeneic lymphocytes or sperm, or by purified protein derivative of tuberculin (PPD), the proportion of positive T cells increased substantially. DRw typing indicated that Ia specificities on activated T cells were not acquired passively from the stimulator cells, suggesting therefore that either "selection" of a small DRw+ cell subset or derepression and/or exposure of DR locus gene products occurs during T cell activation.

UI MeSH Term Description Entries
D007074 Immunoglobulin G The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B. Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D007075 Immunoglobulin M A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally was called a macroglobulin. Gamma Globulin, 19S,IgM,IgM Antibody,IgM1,IgM2,19S Gamma Globulin,Antibody, IgM
D007519 Isoantigens Antigens that exist in alternative (allelic) forms in a single species. When an isoantigen is encountered by species members who lack it, an immune response is induced. Typical isoantigens are the BLOOD GROUP ANTIGENS. Alloantigens,Alloantigen,Isoantigen
D008297 Male Males
D011947 Receptors, Antigen, B-Cell IMMUNOGLOBULINS on the surface of B-LYMPHOCYTES. Their MESSENGER RNA contains an EXON with a membrane spanning sequence, producing immunoglobulins in the form of type I transmembrane proteins as opposed to secreted immunoglobulins (ANTIBODIES) which do not contain the membrane spanning segment. Antigen Receptors, B-Cell,B-Cell Antigen Receptor,B-Cell Antigen Receptors,Surface Immunoglobulin,Immunoglobulins, Membrane-Bound,Immunoglobulins, Surface,Membrane Bound Immunoglobulin,Membrane-Bound Immunoglobulins,Receptors, Antigen, B Cell,Surface Immunoglobulins,Antigen Receptor, B-Cell,Antigen Receptors, B Cell,B Cell Antigen Receptor,B Cell Antigen Receptors,Bound Immunoglobulin, Membrane,Immunoglobulin, Membrane Bound,Immunoglobulin, Surface,Immunoglobulins, Membrane Bound,Membrane Bound Immunoglobulins,Receptor, B-Cell Antigen,Receptors, B-Cell Antigen
D005260 Female Females
D006649 Histocompatibility Antigens A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They determine tissue type for transplantation and cause allograft rejections. The latter are systems of allelic alloantigens that can cause weak transplant rejection. Transplantation Antigens,Antigens, Transplantation,Histocompatibility Antigen,LD Antigens,SD Antigens,Antigen, Histocompatibility,Antigens, Histocompatibility,Antigens, LD,Antigens, SD
D006650 Histocompatibility Testing Identification of the major histocompatibility antigens of transplant DONORS and potential recipients, usually by serological tests. Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (King, Dictionary of Genetics, 4th ed) Crossmatching, Tissue,HLA Typing,Tissue Typing,Crossmatchings, Tissue,HLA Typings,Histocompatibility Testings,Testing, Histocompatibility,Testings, Histocompatibility,Tissue Crossmatching,Tissue Crossmatchings,Tissue Typings,Typing, HLA,Typing, Tissue,Typings, HLA,Typings, Tissue
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000954 Antigens, Surface Antigens on surfaces of cells, including infectious or foreign cells or viruses. They are usually protein-containing groups on cell membranes or walls and may be isolated. Cell Surface Antigens,Surface Antigens,Surface Markers, Immunological,Cell Surface Antigen,Immunologic Surface Markers,Markers, Immunological Surface,Surface Antigen,Surface Markers, Immunologic,Antigen, Cell Surface,Antigen, Surface,Antigens, Cell Surface,Immunological Surface Markers,Markers, Immunologic Surface,Surface Antigen, Cell,Surface Antigens, Cell

Related Publications

M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward
Level of Ia-like antigens on human B and T lymphocytes.
March 1981, Transplantation proceedings,
M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward
The detection of Ia-like and DRw antigens on activated T cells.
December 1979, Transplantation proceedings,
M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward
Discordant expression of human Ia-like antigens on hematopoietic progenitor cells.
May 1984, Journal of immunology (Baltimore, Md. : 1950),
M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward
Ia-like antigens on freshly explanted human melanoma.
May 1981, Clinical immunology and immunopathology,
M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward
Clonal expression of differentiation and Ia-like antigens on alloreactive human T lymphocytes.
April 1984, European journal of immunology,
M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward
Fluorescence visualization of Ia antigens on T cells.
July 1980, Cellular immunology,
M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward
T lymphocytes expressing human Ia-like antigens in infectious mononucleosis (IM).
September 1980, Blood,
M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward
Peripheral human T cells sensitized in mixed leukocyte culture synthesize and express Ia-like antigens.
November 1978, The Journal of experimental medicine,
M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward
HLA-D-associated 'Ia-like' antigens on human macrophages.
January 1977, Scandinavian journal of immunology,
M F Greaves, and W Verbi, and H Festenstein, and C Papasteriadis, and D Jaraquemada, and A Hayward
DR (Ia-like) antigens on human melanoma cells. Serological detection and immunochemical characterization.
March 1979, The Journal of experimental medicine,
Copied contents to your clipboard!