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Pyrophosphate ion-responsive alginate hydrogel as an effective fluorescent sensing platform for alkaline phosphatase detection. 2019
Key Laboratory of Chemical Biology of Jiangxi Province, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang, 330022, P. R. China. hltan@jxnu.edu.cn.
A pyrophosphate ion (PPi)-responsive alginate hydrogel was fabricated by using Cu2+ as a crosslinker. Benefiting from the ultrahigh affinity of Cu2+ to PPi, which can discriminate PPi from phosphate ions and other anions, the incorporation of carbon dots enables the alginate hydrogel to be an effective fluorescent sensing platform for the detection of alkaline phosphatase.
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