-transparent.png){kind=logo}
Inhibition of rabbit skeletal muscle glycogen phosphorylase b by biotin, pyridoxine, lipoic acid, as well as by thiamine and cobalamine vitamins and coenzymes has been found. The values of "half-saturation" concentration and Hill coefficients are determined for biotin (27 mM, 1.3), pyridoxine (19 mM, 1.7), 5'-deoxyadenosyl-cobalamine (2.5 mM, 1.5), lipoic acid (3.4 mM, 1.1), thiamine (11 mM, 1.3), thiamine diphosphate (11 mM, 1.0). Effectiveness of the enzyme inhibition by vitamins and coenzymes containing different heterocyclic groups is analysed; riboflavin and its coenzymic forms are suggested to be the most effective inhibitors.
Related Publications
N I Klinova, and
S V Klinov, and
B I Kurganov, and
S D Mikhno, and
M V Baliakina
March 1995,
Biochemistry and molecular biology international,
N I Klinova, and
S V Klinov, and
B I Kurganov, and
S D Mikhno, and
M V Baliakina
January 1979,
Molekuliarnaia biologiia,
N I Klinova, and
S V Klinov, and
B I Kurganov, and
S D Mikhno, and
M V Baliakina
July 1986,
Biochemistry international,
N I Klinova, and
S V Klinov, and
B I Kurganov, and
S D Mikhno, and
M V Baliakina
December 1980,
Indian journal of biochemistry & biophysics,
N I Klinova, and
S V Klinov, and
B I Kurganov, and
S D Mikhno, and
M V Baliakina
December 1982,
Biochimica et biophysica acta,
N I Klinova, and
S V Klinov, and
B I Kurganov, and
S D Mikhno, and
M V Baliakina
October 2007,
Biochemistry,
N I Klinova, and
S V Klinov, and
B I Kurganov, and
S D Mikhno, and
M V Baliakina
February 1998,
Doklady Akademii nauk,
N I Klinova, and
S V Klinov, and
B I Kurganov, and
S D Mikhno, and
M V Baliakina
January 1980,
Molekuliarnaia biologiia,
N I Klinova, and
S V Klinov, and
B I Kurganov, and
S D Mikhno, and
M V Baliakina
August 2001,
Biophysical chemistry,
N I Klinova, and
S V Klinov, and
B I Kurganov, and
S D Mikhno, and
M V Baliakina
September 1988,
Bioorganicheskaia khimiia,
