Biomaterial Database

An unusual cause of gastrointestinal bleeding: intestinal neurofibromatosis. 1988

K S Jeng, and K C Yang, and H J Ching, and C C Shih

UI	MeSH Term	Description	Entries
D007078	Ileal Neoplasms	Tumors or cancer in the ILEUM region of the small intestine (INTESTINE, SMALL).	Cancer of ILEUM,Cancer of the ILEUM,Cancer, Ileal,Ileal Cancer,Cancers, Ileal,ILEUM Cancer,ILEUM Cancers,Ileal Cancers,Ileal Neoplasm,Neoplasm, Ileal,Neoplasms, Ileal
D007579	Jejunal Diseases	Pathological development in the JEJUNUM region of the SMALL INTESTINE.	Disease, Jejunal,Diseases, Jejunal,Jejunal Disease
D007580	Jejunal Neoplasms	Tumors or cancer in the JEJUNUM region of the small intestine (INTESTINE, SMALL).	Cancer of Jejunum,Cancer of the Jejunum,Cancer, Jejunal,Jejunal Cancer,Cancers, Jejunal,Jejunal Cancers,Jejunal Neoplasm,Jejunum Cancer,Jejunum Cancers,Neoplasm, Jejunal,Neoplasms, Jejunal
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009456	Neurofibromatosis 1	An autosomal dominant inherited disorder (with a high frequency of spontaneous mutations) that features developmental changes in the nervous system, muscles, bones, and skin, most notably in tissue derived from the embryonic NEURAL CREST. Multiple hyperpigmented skin lesions and subcutaneous tumors are the hallmark of this disease. Peripheral and central nervous system neoplasms occur frequently, especially OPTIC NERVE GLIOMA and NEUROFIBROSARCOMA. NF1 is caused by mutations which inactivate the NF1 gene (GENES, NEUROFIBROMATOSIS 1) on chromosome 17q. The incidence of learning disabilities is also elevated in this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1014-18) There is overlap of clinical features with NOONAN SYNDROME in a syndrome called neurofibromatosis-Noonan syndrome. Both the PTPN11 and NF1 gene products are involved in the SIGNAL TRANSDUCTION pathway of Ras (RAS PROTEINS).	Peripheral Neurofibromatosis,Recklinghausen Disease of Nerve,von Recklinghausen Disease,Cafe-au-Lait Spots with Pulmonic Stenosis,Molluscum Fibrosum,NF1 (Neurofibromatosis 1),Neurofibromatosis I,Neurofibromatosis Type 1,Neurofibromatosis Type I,Neurofibromatosis, Peripheral Type,Neurofibromatosis, Peripheral, NF 1,Neurofibromatosis, Peripheral, NF1,Neurofibromatosis, Type 1,Neurofibromatosis, Type I,Pulmonic Stenosis with Cafe-au-Lait Spots,Recklinghausen Disease, Nerve,Recklinghausen's Disease of Nerve,Recklinghausens Disease of Nerve,Watson Syndrome,von Recklinghausen's Disease,Cafe au Lait Spots with Pulmonic Stenosis,Neurofibromatoses, Peripheral,Neurofibromatoses, Type I,Neurofibromatosis, Peripheral,Peripheral Neurofibromatoses,Pulmonic Stenosis with Cafe au Lait Spots,Syndrome, Watson,Type 1 Neurofibromatosis,Type 1, Neurofibromatosis,Type I Neurofibromatoses,Type I, Neurofibromatosis,von Recklinghausens Disease
D006471	Gastrointestinal Hemorrhage	Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.	Hematochezia,Hemorrhage, Gastrointestinal,Gastrointestinal Hemorrhages,Hematochezias
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man