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Two patients with linear scleroderma (en coup de sabre) developed systemic lupus erythematosus (SLE). This association has been well documented in only one previous case. The presence of high titer antibodies to ribonucleoprotein (RNP) initially led to the diagnosis of the mixed connective tissue disease. Development of more serious clinical involvement and antibodies to Sm (case 1) or native deoxyribonucleic acid (nDNA) (case 2) helped establish a diagnosis of SLE. Use of these studies in the differential diagnosis of systemic rheumatic diseases is disucssed briefly. The presence of anti-RNAP antibodies in patients with localized scleroderma may herald a more serious rheumatic disease.
S E Mackel, and
F Kozin, and
L M Ryan, and
K J Sheth, and
R E Jordon
October 1990,
The Journal of rheumatology,
S E Mackel, and
F Kozin, and
L M Ryan, and
K J Sheth, and
R E Jordon
August 1989,
The Journal of rheumatology,
S E Mackel, and
F Kozin, and
L M Ryan, and
K J Sheth, and
R E Jordon
January 2000,
Pediatric dermatology,
S E Mackel, and
F Kozin, and
L M Ryan, and
K J Sheth, and
R E Jordon
April 1994,
Journal of Korean medical science,
S E Mackel, and
F Kozin, and
L M Ryan, and
K J Sheth, and
R E Jordon
January 1964,
Annales medicinae internae Fenniae,
S E Mackel, and
F Kozin, and
L M Ryan, and
K J Sheth, and
R E Jordon
January 1999,
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
S E Mackel, and
F Kozin, and
L M Ryan, and
K J Sheth, and
R E Jordon
September 1965,
Archives of dermatology,
S E Mackel, and
F Kozin, and
L M Ryan, and
K J Sheth, and
R E Jordon
September 1965,
Archives of dermatology,
S E Mackel, and
F Kozin, and
L M Ryan, and
K J Sheth, and
R E Jordon
December 1984,
Annals of the rheumatic diseases,
S E Mackel, and
F Kozin, and
L M Ryan, and
K J Sheth, and
R E Jordon
December 2008,
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases,
