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Eighteen patients with systemic lupus erythematosus (SLE) and proliferative glomerulonephritis, underwent serial serum determinations of C3, C4, and native DNA binding capacity, as well as repeat renal biopsy 7 to 48 months (median 25 months) following initial biopsy. Highly significant correlations were found between serum C3 levels and renal histologic changes (P less than 0.0001), and between serum C3 levels and DNA binding capacity (P less than 0.03). Histologic deterioration correlated with depressed C3 levels, while improvement was associated with normalization of C3 levels. No correlation between renal histologic changes and either serum C4 levels or DNA binding capacity was found. The data suggest that the serum level of C3 is the best index of activity of lupus nephritis.
E H Garin, and
W H Donnelly, and
S T Shulman, and
R Fernandez, and
C Finton, and
R L Williams, and
G A Richard
January 1974,
International urology and nephrology,
E H Garin, and
W H Donnelly, and
S T Shulman, and
R Fernandez, and
C Finton, and
R L Williams, and
G A Richard
December 1977,
Australian and New Zealand journal of medicine,
E H Garin, and
W H Donnelly, and
S T Shulman, and
R Fernandez, and
C Finton, and
R L Williams, and
G A Richard
October 1975,
Annals of the rheumatic diseases,
E H Garin, and
W H Donnelly, and
S T Shulman, and
R Fernandez, and
C Finton, and
R L Williams, and
G A Richard
January 1978,
Godisen zbornik na Medicinskiot fakultet vo Skopje,
E H Garin, and
W H Donnelly, and
S T Shulman, and
R Fernandez, and
C Finton, and
R L Williams, and
G A Richard
June 1984,
The International journal of pediatric nephrology,
E H Garin, and
W H Donnelly, and
S T Shulman, and
R Fernandez, and
C Finton, and
R L Williams, and
G A Richard
April 2019,
Zhongguo shi yan xue ye xue za zhi,
E H Garin, and
W H Donnelly, and
S T Shulman, and
R Fernandez, and
C Finton, and
R L Williams, and
G A Richard
October 1974,
Gut,
E H Garin, and
W H Donnelly, and
S T Shulman, and
R Fernandez, and
C Finton, and
R L Williams, and
G A Richard
May 1982,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
E H Garin, and
W H Donnelly, and
S T Shulman, and
R Fernandez, and
C Finton, and
R L Williams, and
G A Richard
September 1975,
Tropical and geographical medicine,
E H Garin, and
W H Donnelly, and
S T Shulman, and
R Fernandez, and
C Finton, and
R L Williams, and
G A Richard
March 2015,
Clinical rheumatology,
